Results 91 to 100 of about 14,132 (182)

Co‐current filtrate flow in TFF perfusion processes: Decoupling transmembrane pressure from crossflow to improve product sieving

open access: yesBiotechnology and Bioengineering, Volume 121, Issue 2, Page 640-654, February 2024.
Co‐current filtrate flow in tangential flow filtration (TFF) applications can either be operated with stable co‐flow to achieve uniform transmembrane pressure (HPTFF) or with stepping co‐flow generating an alternating and tunable Starling recirculation (scTFF).
Patrick Romann   +8 more
wiley   +1 more source

Fluorescent sensors for activity and regulation of the nitrate transceptor CHL1/NRT1.1 and oligopeptide transporters

open access: yeseLife, 2014
To monitor nitrate and peptide transport activity in vivo, we converted the dual-affinity nitrate transceptor CHL1/NRT1.1/NPF6.3 and four related oligopeptide transporters PTR1, 2, 4, and 5 into fluorescence activity sensors (NiTrac1, PepTrac). Substrate
Cheng-Hsun Ho, Wolf B Frommer
doaj   +1 more source

Leishmanicidal Potential of Hardwickiic Acid Isolated From Croton sylvaticus

open access: yesFrontiers in Pharmacology, 2020
Leishmania is a parasitic protozoon responsible for the neglected tropical disease Leishmaniasis. Approximately, 350 million people are susceptible and close to 70,000 death cases globally are reported annually.
Justice Afrifa Crentsil   +11 more
doaj   +1 more source

The role of folate transport in antifolate drug action in Trypanosoma brucei [PDF]

open access: yes, 2016
The aim of this study was to identify and characterize mechanisms of resistance to antifolate drugs in African trypanosomes. Genome-wide RNAi library screens were undertaken in bloodstream form Trypanosoma brucei exposed to the antifolates methotrexate ...
Ali   +66 more
core   +2 more sources

‘Problems of involvement and detachment’: Norbert Elias and the investigation of contemporary social processes [PDF]

open access: yes, 2017
In this paper, we seek to move beyond dominant interpretations of Elias by drawing attention to an increasing body of work in the fields of social and public policy.
Lever, John, Powell, Ryan
core   +1 more source

Combined Intra- and Inter-domain Traffic Engineering using Hot-Potato Aware Link Weights Optimization [PDF]

open access: yes, 2008
A well-known approach to intradomain traffic engineering consists in finding the set of link weights that minimizes a network-wide objective function for a given intradomain traffic matrix.
Balon, Simon, Leduc, Guy
core   +1 more source

New approaches to Leishmania chemotherapy: pteridine reductase 1 (PTR1) as a target and modulator of antifolate sensitivity

open access: yesParasitology, 1997
Leishmania and other trypanosomatid protozoa require reduced pteridines (pterins and folates) for growth, suggesting that inhibition of these pathways could be targeted for effective chemotherapy. This goal has not yet been realized, indicating that pteridine metabolism may be unusual in this lower eukaryote.
Nare, Bakela   +3 more
openaire   +3 more sources

An engineered mammalian band-pass network [PDF]

open access: yes, 2017
Gene expression circuitries, which enable cells to detect precise levels within a morphogen concentration gradient, have a pivotal impact on biological processes such as embryonic pattern formation, paracrine and autocrine signalling, and cellular ...
Fussenegger, Martin, Greber, David
core  

There\u27s Something Rotten in Film Criticism, and His Name is, Regrettably, Not Johnny [PDF]

open access: yes, 2016
I argue for the development of a middle-ground film criticism, less jargon-filled than academic writing, yet one that uses historical and theoretical methods beyond those found in journalistic, mass media popular criticism.
Metz, Walter C
core   +1 more source

A Narnavirus in the trypanosomatid protist plant pathogen Phytomonas serpens [PDF]

open access: yes, 2016
We describe here a new RNA virus (PserNV1) from the plant protist parasite Phytomonas serpens (family Trypanosomatidae, Kinetoplastida, supergroup Excavata).
Akopyants, Natalia S   +4 more
core   +2 more sources

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