Results 81 to 90 of about 3,370 (132)

Antileishmanial natural products as potential inhibitors of the <i>Leishmania</i> pteridine reductase: insights from molecular docking and molecular dynamics simulations. [PDF]

In Silico Pharmacol
Adomako AK, Gasu EN, Mensah JO, Borquaye LS.   +3 more
europepmc   +1 more source

Antileishmanial potential of thiourea-based derivatives: design, synthesis and biological activity. [PDF]

RSC Adv
Hadi A, Yaqoob M, Hussain F, Al-Kahraman YMSA, Jan MS, Mahmood A, Shier T, Rashid U.   +7 more
europepmc   +1 more source

Isopropyl Gallate, a Gallic Acid Derivative: In Silico and In Vitro Investigation of Its Effects on Leishmania major. [PDF]

Pharmaceutics, 2022
Melo DS, Nery Neto JAO, Santos MSD, Pimentel VD, Carvalho RCV, Sousa VC, Sousa RGC, Nascimento LGD, Alves MMM, Arcanjo DDR, Sousa DP, Carvalho FAA.   +11 more
europepmc   +1 more source

Expanding the repertoire of imine reductases by mining divergent biosynthetic pathways for promiscuous reactivity. [PDF]

Chem Catal
Aleku GA, Hollfelder F.
europepmc   +1 more source

A Hyaluronan and Proteoglycan Link Protein 1 Matrikine: Role of Matrix Metalloproteinase 2 in Multiple Myeloma NF-κB Activation and Drug Resistance. [PDF]

Mol Cancer Res, 2022
Mark C, Warrick J, Callander NS, Hematti P, Miyamoto S.   +4 more
europepmc   +1 more source

Sensitivity Analysis of Pyrenophora tritici-repentis to Quinone-Outside Inhibitor and 14α-Demethylase Inhibitor Fungicides in Latvia. [PDF]

Pathogens
Kaņeps J, Bankina B, Moročko-Bičevska I, Apsīte K, Roga A, Fridmanis D.   +5 more
europepmc   +1 more source

Crystal structure of the ternary complex of Leishmania major pteridine reductase 1 with the cofactor NADP⁺/NADPH and the substrate folic acid. [PDF]

Acta Crystallogr F Struct Biol Commun, 2022
Dello Iacono L, Di Pisa F, Mangani S.
europepmc   +1 more source

Inactivation of the Leishmania tarentolae Pterin Transporter (BT1) and Reductase (PTR1) Genes Leads to Viable Parasites with Changes in Folate Metabolism and Hypersensitivity to the Antifolate Methotrexate

, 2004
Amal El Fadili, Christoph Kündig, Gaétan Roy, Marc Ouellette   +3 more
openalex   +1 more source

Identification of Innovative Folate Inhibitors Leveraging the Amino Dihydrotriazine Motif from Cycloguanil for Their Potential as Anti-<i>Trypanosoma brucei</i> Agents. [PDF]

ACS Infect Dis
Francesconi V, Rizzo M, Pozzi C, Tagliazucchi L, Konchie Simo CU, Saporito G, Landi G, Mangani S, Carbone A, Schenone S, Santarém N, Tavares J, Cordeiro-da-Silva A, Costi MP, Tonelli M.   +14 more
europepmc   +1 more source

Synthesis of thiosemicarbazone Schiff base derivatives as anti-leishmanial agents and molecular dynamics simulations insights. [PDF]

Sci Rep
Molaei S, Shiran JA, Shakour N, Baradaran M, Malihi Z, Rahimi MR, Zal YA, Sepehri S.   +7 more
europepmc   +1 more source