Results 101 to 110 of about 10,062 (208)

COUNTERREGULATORY EFFECTS OF PTX3 ON INFLAMMATION AND CELLULAR AGING [PDF]

, 2018
Pentraxin 3 (PTX3) is a vital regulator of innate immune function that has been shown to counterregulate pro-inflammatory signaling and protect against the development of cardiovascular disease (CVD). Less is known about how PTX3 may mitigate against CVD
Slusher, Aaron L.
core   +1 more source

Suppression of pentraxin 3 inhibits human osteosarcoma cell metastasis by repressing MAZ through STAT3 pathway

Cancer Cell International
Background Pentraxin 3 (PTX3), also known as TNF-inducible gene 14 protein (TSG-14), exerts pleiotropic roles in inflammation, immune responses, and a myriad of cancers, but there is limited knowledge regarding the role of PTX3 in the metastasis of human
Chia-Hsuan Chou, Yi-Hsien Hsieh, Pei-Ni Chen, Jia-Sin Yang, Chih-Hsin Tang, Shun-Fa Yang, Ko-Hsiu Lu   +6 more
doaj   +1 more source

PTX3 is increased in human allergic asthma.

, 2013
Positive PTX3-immunoreactivity is shown from representative bronchial biopsies of healthy control (A), mild (C), moderate (E), and severe (G) asthma subjects. No staining was observed in isotype-matched control mAbs in corresponding biopsies (B, D, F, or
Abdelilah S. Gounni (89329), Latifa Koussih (326043), Lianyu Shan (89326), Jamila Chakir (309142), Naresh Singh Redhu (326044), Jingbo Zhang (326042), Andrew J. Halayko (183293)   +6 more
core   +1 more source

PTX3 is expressed in terminal lymphatics and shapes their organization and function

Frontiers in Immunology
IntroductionThe lymphatic system is a multifaceted regulator of tissue homeostasis and an integral part of immune responses. Previous studies had shown that subsets of lymphatic endothelial cells (LEC) express PTX3, an essential component of humoral ...
Andrea Doni, Marina Sironi, Annalisa Del Prete, Annalisa Del Prete, Fabio Pasqualini, Sonia Valentino, Ivan Cuccovillo, Raffaella Parente, Michela Calvi, Antonella Tosoni, Gianluca Vago, Manuela Nebuloni, Cecilia Garlanda, Cecilia Garlanda, Annunciata Vecchi, Barbara Bottazzi, Alberto Mantovani, Alberto Mantovani, Alberto Mantovani   +18 more
doaj   +1 more source

Human pentraxin 3 binds to the complement regulator c4b-binding protein.

PLoS ONE, 2011
The long pentraxin 3 (PTX3) is a soluble recognition molecule with multiple functions including innate immune defense against certain microbes and the clearance of apoptotic cells.
Anne Braunschweig, Mihály Józsi
doaj   +1 more source

Zur Rolle des langen Pentraxins PTX3 in der Pathogenese des Systemischen Lupus Erythematodes [PDF]

, 2014
Der SLE ist eine Autoimmunerkrankung aus der Gruppe der Kollagenosen, in deren Verlauf es durch einen Toleranzverlust zu einer fälschlichen Antwort des Immunsystems auf körpereigene Strukturen kommt.
Roemmele, Christoph Frieder
core   +1 more source

Role of PTX3 in Cystic Fibrosis-associated infections [PDF]

, 2011
PTX3, a soluble innate immunity receptor, binds to selected microbes and facilitates their clearance by phagocytes. PTX3 selectively binds to Pseudomonas aeruginosa and Aspergillus fumigatus, two microorganisms frequently colonizing the airways of ...
Bouchara, Jean-Philippe, Person, Christine, C. Person, Hamon, Yveline, Delneste, Yves, J.L. Giniès, Y. Delneste, Giniès, Jean-Louis, Y. Hamon, J.P. Bouchara   +9 more
core  

Inactivation of pentraxin 3 suppresses M2-like macrophage activity and immunosuppression in colon cancer

Journal of Biomedical Science
Background The tumor microenvironment is characterized by inflammation-like and immunosuppression situations. Although cancer-associated fibroblasts (CAFs) are among the major stromal cell types in various solid cancers, including colon cancer, the ...
Feng-Wei Chen, Yung-Ling Wu, Chao-Chun Cheng, Yu-Wei Hsiao, Jhih-Ying Chi, Liang-Yi Hung, Chih-Peng Chang, Ming-Derg Lai, Ju-Ming Wang   +8 more
doaj   +1 more source

PTX3 abrogates FGF-2 induced HASMC migration.

, 2013
Boyden upper chamber-seeded HASMC were exposed to graded concentrations of (A) PTX3, (B) FGF-2, and (C) PTX3 plus FGF-2 (20 ng/ml) in lower compartment for 4 h. The migrated cells were quantified by light microscope (magnification, ×200).
Abdelilah S. Gounni (89329), Latifa Koussih (326043), Lianyu Shan (89326), Jamila Chakir (309142), Naresh Singh Redhu (326044), Jingbo Zhang (326042), Andrew J. Halayko (183293)   +6 more
core   +1 more source

PTX3: a new mediator of bone metabolism and osteoporosis [PDF]

Muscle, Ligaments and Tendons Journal, 2017
Tarantino U., Feola M., Celi M., Scimeca M.   +3 more
openaire   +5 more sources