Results 91 to 100 of about 10,062 (208)

Hyaluronan in Ocular Surface Health and Disease: From Biological Mechanisms to Therapeutic Applications

Proteoglycan Research, Volume 4, Issue 4, October 2026.
ABSTRACT Hyaluronan (HA) is an ubiquitous non‐sulfated glycosaminoglycan with unique physicochemical and biological properties that underpin its essential roles in tissue homeostasis, repair, and diseases. First identified in the vitreous humor of the eye, HA has a long‐standing history in ophthalmology as a key component of ophthalmic visco‐surgical ...
Sudhir Verma, Mohammed Salman, Eduardo Cilli, Vivien Coulson‐Thomas   +3 more
wiley   +1 more source

CD31+ Cell Enrichment Enhances Therapeutic Effects of Stromal Vascular Fraction in Experimental Primary Osteoarthritis: A Preclinical Study in the Dunkin Hartley Guinea Pig Model

Advanced Science, Volume 13, Issue 51, 14 September 2026.
Both SVF and CD31+ SVF improve spontaneous osteoarthritis, but CD31+ enrichment refines the therapeutic profile rather than broadly enhancing all effects. More distinct benefits are observed in extracellular matrix remodeling, osteochondral integrity, and subchondral/trabecular bone preservation, supporting CD31+‐enriched SVF as a biologically enhanced
Sijia Zhou, Tobias Winkler, Bin Chen, Marta Grzeski, Yilong Yang, Florian N. Fleckenstein, Dominik Geisel, Alexander Hildebrandt, Daniela Aschenbrenner, Marie Agatha Mohn, Benjamin Claass, January Weiner 3rd, Sven Geissler, Georg N. Duda, Søren P. Sheikh, Oliver Klein, Tazio Maleitzke   +16 more
wiley   +1 more source

ELISA Data (PTX3 IL17 and IFN)

, 2015
Data from PTX3, IL-17 and IFN-gamma ...
Deepali Kumar (127169), Rhea Pavan (716816), Atul Humar (127170), Rupert Kaul (34935), Matthew Seftel (716818), Alyajahan Bhimji (716815), Jose F. Camargo (271023), Vikas Gupta (20712), Andre Schuh (716817), Jeffrey H. Lipton (716819), Shahid Husain (529516)   +10 more
core   +1 more source

Longitudinal analysis of anti-PTX3 aAbs.

, 2016
Anti-PTX3 aAbs were analysed by ELISA in 14 patients with active disease (onset or relapse) and at remission. Results are expressed in OD values. Dotted line corresponds to mean + 2 SD titres of anti-PTX3 aAbs in HS sera; full line corresponds to the ...
Alberto Mantovani (287283), Pascale Jeannin (132724), Simon Blanchard (132689), Gilles Renier (5666545), Alain Chevailler (847264), Barbara Bottazzi (291673), Jean-François Augusto (437047), Pascale Pignon (217001), Jean-François Subra (437051), Xavier Puéchal (3519929), Sébastien Jaillon (5666542), Philippe Guilpain (847263), Amélie Simon (561052), Yves Delneste (132672), Erwan Garo (132696)   +14 more
core   +1 more source

Increased Serum Pentraxin 3 Levels are Associated with Poor Prognosis of Hepatitis B Virus-Related Hepatocellular Carcinoma

Journal of Hepatocellular Carcinoma, 2021
Qunying Han,1 Huan Deng,1 Xiude Fan,1 Xiaoyun Wang,1 Xiaoge Zhang,1 Kun Zhang,1 Na Li,1 Yi Lv,2,3 Zhengwen Liu1,3 1Department of Infectious Diseases, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi, People’s Republic of China ...
Han Q, Deng H, Fan X, Wang X, Zhang X, Zhang K, Li N, Lv Y, Liu Z   +8 more
doaj  

Epigenetic regulation of the extrinsic oncosuppressor PTX3 gene in inflammation and cancer

OncoImmunology, 2017
PTX3 is a component of the humoral arm of innate immunity and an extrinsic oncosuppressor gene taming tumor-promoting inflammation. Here, we show that two enhancers differently regulate PTX3 expression: enhancer 1, located 230 kb upstream of PTX3 ...
Marcello Rubino, Paolo Kunderfranco, Gianluca Basso, Carolina Magdalen Greco, Fabio Pasqualini, Simone Serio, Massimo Roncalli, Luigi Laghi, Alberto Mantovani, Roberto Papait, Cecilia Garlanda   +10 more
doaj   +1 more source

The Long Pentraxin 3 Plays a Role in Bone Turnover and Repair

Frontiers in Immunology, 2018
Pentraxin 3 (PTX3) is an inflammatory mediator acting as a fluid-phase pattern recognition molecule and playing an essential role in innate immunity and matrix remodeling.
Danka Grčević, Danka Grčević, Marina Sironi, Sonia Valentino, Livija Deban, Livija Deban, Hrvoje Cvija, Hrvoje Cvija, Antonio Inforzato, Antonio Inforzato, Nataša Kovačić, Nataša Kovačić, Vedran Katavić, Vedran Katavić, Tomislav Kelava, Tomislav Kelava, Ivo Kalajzić, Alberto Mantovani, Alberto Mantovani, Alberto Mantovani, Barbara Bottazzi   +20 more
doaj   +1 more source

Correlations between PTX3 and each parameter.

, 2018
Correlations between PTX3 and each parameter.
Yuichi Takashi (5158901), Masao Omura (799104), Tetsuo Nishikawa (2987), Minae Koga (5158904), Jun Saito (2475391), Yoko Matsuzawa (1838167)   +5 more
core   +1 more source

Human renal epithelial cells produce the long pentraxin PTX3

, 2005
Human renal epithelial cells produce the long pentraxin PTX3.BackgroundPentraxin 3 (PTX3) is a prototypic long pentraxin with structural similarities in the C-terminal domain to the classical short pentraxins C-reactive protein (CRP) and serum amyloid P ...
Simone De Haij, C. van Kooten, Cees Van Kooten, M. R. Daha, B. Bottazzi, Alma J. Nauta, J. Aten, Maria C. Borrias, Maria Pia Rastaldi, M. P. Rastaldi, Barbara Bottazzi, Mohamed R. Daha, A. Roos, Alberto Mantovani, M. C. Borrias, Jan Aten, A. Mantovani, Anja Roos, S. de Haij, A. J. Nauta   +19 more
core   +1 more source

Plasma Pentraxin3 is a Novel Marker for Nonalcoholic Steatohepatitis (NASH)

BMC Gastroenterology, 2008
Background The changes in the liver in nonalcoholic fatty liver disease (NAFLD) range over a wide spectrum, extending from steatosis to steatohepatitis (NASH).
Saito Satoru, Kubota Kensuke, Kobayashi Noritoshi, Nozaki Yuichi, Inamori Masahiko, Kirikoshi Hiroyuki, Takahashi Hirokazu, Iida Hiroshi, Mawatari Hironori, Yoneda Kyoko, Fujita Koji, Endo Hiroki, Kato Shingo, Uchiyama Takashi, Yoneda Masato, Maeyama Shiro, Sagara Mina, Aburatani Hiroyuki, Kodama Tatsuhiko, Nakajima Atsushi   +19 more
doaj   +1 more source