Results 81 to 90 of about 10,062 (208)
TNFSF14/LIGHT responses in intestinal and oesophageal fibroblasts are differentially modulated by hydroxylase inhibitors
The Journal of Physiology, EarlyView.Abstract figure legend LIGHT is a mutual mediator of intestinal and oesophageal fibroblast inflammation with common as well as tissue‐specific effects. Hydroxylase inhibitors can selectively suppress inflammatory factors in both cell types, albeit targeting different signalling pathways.Cian M. Ohlendieck, Carlos Matellan, Cristina Bauset, Bella Raphael, Mary Nwaezeigwe, Emer Flynn, Kevin Okamoto, Desmond Winter, Colm Collins, Katie Doogan, Seán T. Martin, Glen Doherty, Seema S. Aceves, Mario C. Manresa +13 morewiley +1 more sourcePrepartum Heat Stress Dysregulates Immune Resilience in Postpartum Dairy Cows
The FASEB Journal, Volume 40, Issue 20, 31 October 2026.Increasing environmental temperatures pose a major challenge to animal welfare by inducing heat stress and increasing the incidence of disease. Immune resilience is essential for maintaining animal health; however, the mechanisms linking heat stress to immune dysfunction and disease remain unclear.Arslan Tariq, Masroor Sagheer, Nicholas C. Kertz, Zachary K. Seekford, Maria A. T. de Bari, Gabriela A. Macay, Sriniwas Pandey, Yuting Zhai, Kwangcheol C. Jeong, Geoffrey E. Dahl, John J. Bromfield +10 morewiley +1 more sourcePTX3 and SAP bind to overlapping sites on leukocytes.
, 2015 A) Human Leukocytes were incubated with 1 μg/ml unlabeled PTX3, SAP, or human IgG Fc for 30 minutes at 4°C. Cells were then incubated with 1 μg/ml labelled PTX3, for an additional 30 minutes at 4°C.Richard H. Gomer (214653), J. Sjef Verbeek (237095), Darrell Pilling (68014), Nehemiah Cox (307503), Varsha Vakil (65341) +4 morecore +1 more sourceUnveiling Endotypes in Systemic Lupus Erythematosus Through Multiomic Analysis: Insights Into Cardiovascular and Renal Complications
Arthritis &Rheumatology, Volume 78, Issue 10, Page 2124-2137, October 2026.Objective
Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.Tomás Cerdó, Laurel Woodridge, Sagrario Corrales, Juan Rafael Muñoz‐Castañeda, Ana Isabel Torralbo, Anisur Rahman, Filipa Farinha, Rafaela Ortega Castro, Pedro Segui, Ismael Sanchez‐Pareja, Laura Muñoz‐Barrera, Christian Merlo, Desiree Ruiz‐Vilchez, M. Carmen Ábalos‐Aguilera, Pilar Font, Nuria Barbarroja Puerto, PRECISESADS Clinical Consortium, Lorenzo Beretta, Barbara Vigone, Jacques‐Olivier Pers, Alain Saraux, Valérie Devauchelle‐Pensec, Divi Cornec, Sandrine Jousse‐Joulin, Bernard Lauwerys, Julie Ducreux, Anne‐Lise Maudoux, Carlos Vasconcelos, Ana Tavares, Esmeralda Neves, Raquel Faria, Mariana Brandão, Ana Campar, António Marinho, Fátima Farinha, Isabel Almeida, Miguel Angel Gonzalez‐Gay Mantecón, Ricardo Blanco Alonso, Alfonso Corrales Martínez, Ricard Cervera, Ignasi Rodríguez‐Pintó, Gerard Espinosa, Rik Lories, Ellen De Langhe, Nicolas Hunzelmann, Doreen Belz, Torsten Witte, Niklas Baerlecken, Georg Stummvoll, Michael Zauner, Michaela Lehner, Eduardo Collantes, Ma Carmen Castro‐Villegas, Norberto Ortego, María Concepción Fernández Roldán, Enrique Raya, Inmaculada Jiménez Moleón, Enrique de Ramon, Isabel Díaz Quintero, Pier Luigi Meroni, Maria Gerosa, Tommaso Schioppo, Carolina Artusi, Carlo Chizzolini, Aleksandra Zuber, Donatienne Wynar, Laszló Kovács, Attila Balog, Magdolna Deák, Márta Bocskai, Sonja Dulic, Gabriella Kádár, Falk Hiepe, Velia Gerl, Silvia Thiel, Manuel Rodriguez Maresca, Antonio López‐Berrio, Rocío Aguilar‐Quesada, Héctor Navarro‐Linares, Marta Alarcón‐Riquelme, Alejandro Escudero‐Contreras, M. Ángeles Aguirre‐Zamorano, Carlos Perez‐Sanchez, Elizabeth C. Jury, Chary Lopez‐Pedrera +84 morewiley +1 more sourcePTX3 interacts with inter-alpha-trypsin inhibitor - Implications for hyaluronan organization and cumulus oophorus expansion
, 2007 Pentraxin 3 (PTX3) and heavy chains (HCs) of inter-alpha-trypsin inhibitor (I alpha I) are essential for hyaluronan ( HA) organization within the extracellular matrix of the cumulus oophorus, which is critical for in vivo oocyte fertilization and female ...Camaioni, A, SIRACUSA, GREGORIO, Livija Deban, CAMAIONI, ANTONELLA, Salustri, A, Siracusa, G, SALUSTRI, ANTONIETTA, Andrea Doni, Veronica Negri, Salvatori, G, Antonella Camaioni, Antonio Bastone, Bastone, A, Deban, L, Barbara Bottazzi, Scarchilli, L, Alberto Mantovani, Negri, V, Laura Scarchilli, Gregorio Siracusa, Bottazzi, B, Doni, A, Giovanni Salvatori, Antonietta Salustri, Mantovani, A +24 morecore +1 more sourceDataset related to article "The Long Pentraxin PTX3 Controls Klebsiella Pneumoniae Severe Infection "
, 2022 This record contains raw data related to article “The Long Pentraxin PTX3 Controls Klebsiella Pneumoniae Severe Infection"
Klebsiella pneumoniae is a common pathogen in human sepsis. The emergence of multidrug-resistant K.Fatemeh Asgari, Alessia Giordano, Raffaella Parente, Fabio Pasqualini, Matteo Stravalaci, Nadia Polentarutti, Cornelis Van't Veer, Alberto Mantovani, Federica Riva, Chiara Perucchini, Sadaf Davoudian, Domenico Supino, Andrea Doni, Elena Magrini, Thierry Roger, Sebastien Jaillon, Remi Porte, Andrea Mariancini, Camilla Recordati, Cecilia Garlanda, Marialuisa Barbagallo +20 morecore +1 more sourceGenetic PTX3 Deficiency and Aspergillosis in Stem-Cell Transplantation [PDF]
New England Journal of Medicine, 2014 The soluble pattern-recognition receptor known as long pentraxin 3 (PTX3) has a nonredundant role in antifungal immunity. The contribution of single-nucleotide polymorphisms (SNPs) in PTX3 to the development of invasive aspergillosis is unknown.We screened an initial cohort of 268 patients undergoing hematopoietic stem-cell transplantation (HSCT) and ...Cunha, Cristina, Aversa, Franco, Lacerda, João F, Busca, Alessandro, Kurzai, Oliver, Grube, Matthias, Löffler, Jürgen, Maertens, Johan A, Bell, Alain S, Inforzato, Antonio, Barbati, Elisa, Almeida, Bruno, Santos e. Sousa, Pedro, Barbui, Anna, POTENZA, Leonardo, Caira, Morena, Rodrigues, Fernando, Salvatori, Giovanni, Pagano, Livio, LUPPI, Mario, Mantovani, Alberto, Velardi, Andrea, Romani, Luigina, Carvalho, Agostinho +23 moreopenaire +4 more sourcesOocyte–cumulus cell interaction: a key factor in early embryo development
Biological Reviews, Volume 101, Issue 5, Page 2265-2278, October 2026.ABSTRACT
The evaluation of oocyte competence is a fundamental step in achieving successful outcomes following assisted reproduction techniques (ART). At present, however, conventional oocyte maturation assessment is carried out by morphological observation, which is a subjective method that does not consider molecular features.Marc Torres‐Garrido, Marc Yeste, Yentel Mateo‐Otero +2 morewiley +1 more sourcePTX3 Polymorphisms and Invasive Mold Infections after Solid Organ Transplantation [PDF]
, 2015 Donor PTX3 polymorphisms were shown to influence the risk of invasive aspergillosis among hematopoietic stem cell transplant recipients. Here, we show that PTX3 polymorphisms are independent risk factors for invasive mold infection among 1101 solid organ Khanna, N., Boggian, K, Cusini, A., Lecompte, T. Doco, Manuel, O, Mueller, N.J., Lecompte, T Doco, Hirsch, Hans, Rueger, S., Meylan, Pascal, Pascual, M, Meylan, P. R., Berger, C, van Delden, C, Berger, Christoph, van Delden, C., Meylan, Pascal R, Khanna, N, Khanna, Nina, Garzoni, Christian, Pascual, Manuel, Bochud, P. Y., Wójtowicz, A, Bochud, P-Y, Wojtowicz, A., Manuel, Oriol, Garzoni, C., Hirsch, H., Manuel, O., Bibert, S, Swiss Transplant Cohort, Study, Berger, C., Lecompte, T. D., Bibert, S., Bochud, P.Y., Pascual, Manuel Antonio, Boggian, Katia, Cusini, Alexia, Meylan, P.R., Meylan, P R, Mueller, N. J., Mueller, N J, Mueller, Nicolas J, Wójtowicz, Agnieszka, Beldi, Guido, Swiss Transplant, Cohort Study, Bibert, Stephanie, Boggian, K., Lecompte, T.D., Hirsch, H, Bochud, Pierre-Yves, van Delden, Christian, Rüeger, Sina, Semmo, Nasser, Rüeger, S, Pascual, M., van Delden C, Bochud PY, Hirsch H, Pascual M, Bibert S, Berger C, Boggian K, Mueller NJ, Khanna N, Garzoni C, Rüeger S, Manuel O, Cusini A, Lecompte TD, Meylan PR, Wójtowicz A +71 morecore +3 more sourcesIschemic Stroke and Traumatic Brain Injury: Epidemiology, Molecular Pathways, and Emerging Therapies
MedComm, Volume 7, Issue 10, October 2026.Schematic overview of secondary brain injury after ischemic stroke and traumatic brain injury. Both conditions trigger endothelial cell dysfunction, pericyte contraction, and upregulated AQP4 expression in astrocytic end‐feet, leading to blood–brain barrier disruption.Mengzhao Feng, Qi Qin, Fang Wang, Kaiyuan Zhang, Zhihua Li, Junlei Chang, Min Yu, Fuyou Guo +7 morewiley +1 more source
