Results 71 to 80 of about 10,062 (208)

Local Low‐Frequency Vibration Enhances Wound‐Healing and Modulates Cellular Senescence in Tissues and Exudates in a Hyperglycemic Rat Model

The Journal of Dermatology, EarlyView.
ABSTRACT Hard‐to‐heal wounds, such as diabetic foot ulcers and pressure injuries, pose major clinical challenges due to chronic inflammation and cellular senescence. Cellular senescence‐associated mechanisms, including stress‐responsive p53/p21 signaling and senescence‐associated secretory phenotype‐related inflammation, contribute to impaired wound ...
Daijiro Haba, Chihiro Takizawa, Qi Qin, Sanai Tomida, Ai Horinouchi, Hiromi Sanada, Gojiro Nakagami   +6 more
wiley   +1 more source

PTX3 concentration in CSF based on pathogen.

, 2023
The present study describes diagnostic and prognostic abilities of Cerebrospinal fluid (CSF) Pentraxin 3 (PTX3) in central nervous system (CNS) infections. CSF PTX3 was measured retrospectively from 174 patients admitted under suspicion of CNS infection.
Casper Roed (195185), Lennart Jan Friis-Hansen (14709831), Lea Munthe-Fog (51781), Thore Hillig (14709828), Zitta Barrella Harboe (9964491), Christian Thomas Brandt (8494491), Pelle Trier Petersen (14709825), Martin Munthe Thomsen (14709822)   +7 more
core   +1 more source

Pentraxin 3 promotes the expression of pro-inflammatory cytokines and the migration of macrophages in myocarditis

BMC Cardiovascular Disorders
Background This study aims to investigate the expression of Pentraxin 3 (PTX3) and Nod-like receptor family pyrin domain-containing 3 (NLRP3) in myocarditis and to elucidate their roles and potential interplay in the pathogenesis of myocarditis.
Tianyu Zhu, Ying Ding, Xiaohui Wu, Yan Li, Guanliang Cheng, Ning Wang, Quan Yang, Wenchao Zhang, Xuezhi Chen, Xiaohui Liu   +9 more
doaj   +1 more source

Pentraxin 3 regulated by miR-224-5p modulates macrophage reprogramming and exacerbates osteoarthritis associated synovitis by targeting CD32

Cell Death and Disease, 2022
Emerging evidence has shown an imbalance in M1/M2 macrophage polarization to play an essential role in osteoarthritis (OA) progression. However, the underlying mechanistic basis for this polarization is unknown.
Jianbin Yin, Hua Zeng, Kai Fan, Haoyu Xie, Yan Shao, Yuheng Lu, Jinjian Zhu, Zihao Yao, Liangliang Liu, Hongbo Zhang, Bingsheng Luo, Xinjie Wang, Chun Zeng, Xiaochun Bai, Haiyan Zhang, Daozhang Cai   +15 more
doaj   +1 more source

Adenosine—A Regulator of Human Testicular Peritubular Cells

Andrology, EarlyView.
ABSTRACT Background Extracellular purines, in particular ATP and adenosine, are regulators of physiological and pathophysiological processes throughout the human body. Roles in the human testis are emerging and include actions on peritubular cells, which form the wall of seminiferous tubules.
Lina Scholz, Annika Liebich, Youli Stepanov, Jan B. Stöckl, Mirko Peitzsch, Michaela Schneider, Julia Schneider, Nicole Kreitmair, Matthias Trottmann, Frank‐Michael Köhn, Jovica Ninkovic, Thomas Fröhlich, Artur Mayerhofer   +12 more
wiley   +1 more source

Dataset related to article "Regulation of inflammation and protection against invasive pneumococcal infection by the long pentraxin PTX3"

, 2023
<p>This record contains raw data related to article "Regulation of inflammation and protection against invasive pneumococcal infection by the long pentraxin PTX3". </p><p><strong>Abstract</strong></p><p>< ...
Recordati, Camilla, Silva-Gomes, Rita, Theroude, Charlotte, Asgari, Fatemeh, Bottazzi, Barbara, Mantovani, Alberto, Asselta, Rosanna, Obando, Ignacio, Rodriguez-Gallego, Carlos, Porte, Rémi, Doni, Andrea, Inforzato, Antonio, Valentino, Sonia, Colino, Elena, Pasqualini, Fabio, Monari, Marta Noemi, Sironi, Marina, Parente, Raffaella   +17 more
core   +1 more source

Transcriptome Analysis Reveals Distinct Molecular Signatures Between Erosive and Non‐Erosive Oral Lichen Planus

Oral Diseases, EarlyView.
ABSTRACT Objectives To identify molecular mechanisms distinguishing the erosive subtype of oral lichen planus (EOLP) from the non‐erosive subtype (NEOLP) through transcriptomic analysis. Methods We analysed bulk RNA‐seq data from 30 buccal mucosa samples (13 EOLP, 17 NEOLP) using differential expression, Gene Set Enrichment Analysis (GSEA ...
Kisung Sheen, Chaerim Song, Kanghyun Kwon, Seoyeon Kim, Hye‐Ji Park, Man S. Kim   +5 more
wiley   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

Microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases

Periodontology 2000, EarlyView.
Abstract Objectives To critically evaluate the current evidence on microbial and host‐derived biomarkers for the diagnosis and management of peri‐implant diseases, with emphasis on their biological relevance, potential clinical utility, and current translational limitations.
Su Sheng Quach, Ausra Ramanauskaite, Sašo Ivanovski, Pingping Han, Frank Schwarz, Emilio A. Cafferata   +5 more
wiley   +1 more source

Antiviral activity of the long chain pentraxin PTX3 against influenza viruses

, 2008
Proteins of the innate immune system can act as natural inhibitors of influenza virus, limiting growth and spread of the virus in the early stages of infection before the induction of adaptive immune responses.
L. Romani, B. Bottazzi, A. Mantovani, M. Tate, E. R. Job, P. C. Reading, E. C. Crouch, B. Gilbertson, L. E. Brown, A. G. Brooks, S. Bozza, S. Moretti   +11 more
core   +1 more source