Purpose: to determine the relationship between the functional state of the pituitary-thyroid system and the growth hormone/insulin-like growth factor type 1 (GH/IGF-1) system in adolescents with type 1 diabetes mellitus (DM1) during puberty Material &
Svitlana Turchina +4 more
doaj +1 more source
Cross-Sectional and Longitudinal Examination of Insulin Sensitivity and Secretion across Puberty among Non-Hispanic Black and White Children [PDF]
Background Few studies using criterion measures of insulin sensitivity (SI) and insulin secretory capacity (ISC) have been conducted across puberty to adulthood. We examined how SI and ISC change from pre-puberty through adulthood.
Shannon E. Marwitz +7 more
doaj +1 more source
The paper presents the selected results of a research study of self-efficacy among students of teacher training for primary schools concerning education on puberty by comparing the Czech Republic and Croatia.
Miluše Rašková +2 more
doaj +1 more source
Background: Puberty is an essential milestone in a person’s life. Studies show that precocious puberty is more common in girls than in boys. Objectives: The aim of this study was to survey the causes of precocious puberty in children referred to the ...
Fatemeh Saffari +2 more
doaj +1 more source
Is precocious puberty linked to hypothalamic expression of arginine-phenylalanine-amide-related peptide? [PDF]
The up-regulator regulation and down-regulator regulation of gonadotropin-releasing hormone (GnRH) in central precocious puberty is not yet known. However, recent advances in neuroendocrinology have shown the controlling role of arginine-phenylalanine ...
Yuanyuan He, Wen Sun, Jian Yu
doaj +1 more source
Effects of High-Fat Diet During Childhood on Precocious Puberty and Gut Microbiota in Mice
Precocious puberty mostly stems from endocrine disorders. However, more and more studies show that a high-fat diet (HFD) is closely related to precocious puberty, but its mechanism is unknown. Since gut microbiota is associated with hormone secretion and
Tingbei Bo +11 more
doaj +1 more source
Environmental Exposures during Puberty: Window of Breast Cancer Risk and Epigenetic Damage. [PDF]
During puberty, a woman's breasts are vulnerable to environmental damage ("window of vulnerability"). Early exposure to environmental carcinogens, endocrine disruptors, and unhealthy foods (refined sugar, processed fats, food additives) are hypothesized ...
Aljaber, Dana +19 more
core +1 more source
Enhanced at puberty 1 (EAP1) is a new transcriptional regulator of the female neuroendocrine reproductive axis [PDF]
The initiation of mammalian puberty and the maintenance of female reproductive cycles are events controlled by hypothalamic neurons that secrete the decapeptide gonadotropin-releasing hormone (GnRH).
Sabine Heger +56 more
core +1 more source
Substance P regulates puberty onset and fertility in the female mouse [PDF]
Puberty is a tightly regulated process that leads to reproductive capacity. Kiss1 neurons are crucial in this process by stimulating GnRH, yet how Kiss1 neurons are regulated remains unknown. Substance P (SP), an important neuropeptide in pain perception,
Carroll, R.S. +7 more
core +1 more source
Letrozole treatment of pubertal female mice results in activational effects on reproduction, metabolism and the gut microbiome. [PDF]
Polycystic ovary syndrome (PCOS) is a common endocrine disorder in reproductive-aged women that is comprised of two out of the following three features: hyperandrogenism, oligo- or amenorrhea, or polycystic ovaries. In addition to infertility, many women
Arroyo, Pablo +4 more
core +2 more sources

