Results 131 to 140 of about 2,220,873 (330)

Monogenic and syndromic obesity in children: Clinical recognition, genetics, and precision management

Pediatric Investigation, EarlyView.
Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil, Eugene Feigin, Hussein Zaitoon   +2 more
wiley   +1 more source

Macroglossia: An Uncommon Manifestation of Primary Hypothyroidism due to Hashimoto's Thyroiditis in a Teenage Child

Journal of the ASEAN Federation of Endocrine Societies, 2017
Thyroid disorders are prevalent in the paediatric population and untreated hypothyroidism leads to several adverse consequences like mental retardation, neurological impairment, short stature, delayed puberty and increased morbidity.
Manish Gutch, Annesh Bhattacharjee, Kumar Sukriti, Arpit Gupta, Rao Somendra Singh   +4 more
doaj  

Differences in female athlete triad risk factors between Japanese and American female runners: A comparative study

PM&R, EarlyView.
Abstract Background Differences in female athlete triad risk factors between runners from Japan and the United States have not been explored. Objective To compare the prevalence of Triad risk factors and Triad components between female Japanese and American distance runners. Design Observational, cross‐sectional.
Ana Carla C. Salamunes, Natsue Koikawa, Nancy I. Williams, Kristen J. Koltun, Maha L. Vijaya Krishnan, Yuko Sakurama, Takao Matsuda, Shihoko Suzuki, Yuji Takazawa, Mary Jane De Souza   +9 more
wiley   +1 more source

From biological marker to clinical application: the role of anti-Müllerian hormone for delayed puberty and idiopathic non-obstructive azoospermia in males

Endocrine Connections
Anti-Müllerian hormone (AMH), a biomarker secreted by Sertoli cells in the testes, has emerged as a critical indicator of male reproductive function with significant clinical application potential.
Yuanyuan Zeng, Guicheng Zhao, Yi Zheng, Xiaohui Jiang   +3 more
doaj   +1 more source

Assessment of Oxidative Stress, Vitellogenin, and Human Health Risks Derived From Nile Tilapia Exposed to Metals and Metalloids in Southeastern Brazil

Environmental Toxicology, EarlyView.
ABSTRACT Urban coastal lagoons are highly vulnerable ecosystems increasingly affected by metal contamination, as well as multiple anthropogenic stressors. This study evaluated ecotoxicological and human health risks associated with chronic metal exposure in Nile tilapia (Oreochromis niloticus) from an anthropogenically impacted lagoon in southeastern ...
Julia Araújo Alves, Priscila M. O. Muniz Cunha, Shênia Patrícia Corrêa Novo, Lorena Oliveira Souza Soares, Tatiana Dillenburg Saint‐Pierre, Fábio Veríssimo Correia, André Luís de Sá Salomão, Rachel Ann Hauser‐Davis, Enrico Mendes Saggioro   +8 more
wiley   +1 more source

Worldwide Burden of Hearing Loss Across Childhood and Adolescence, 1990–2021, and Projection to 2050

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives This article aims to analyze the trends in hearing loss (HL) prevalence and years lived with disability (YLDs) in children and adolescents from 1990 to 2021, and the corresponding health inequalities, decomposing causes, and future trends.
Jiao Zhang, Da‐Yong Wang, Xiao‐Nan Wu, Jin Li, Chang‐Shuo Shan, Yu‐Di‐Yang Ma, Chun‐Yan Liu, Yao‐Hua Tian, Qiu‐Ju Wang   +8 more
wiley   +1 more source

Monitoring Serum Testosterone Levels on Androgen Therapy with Long-Acting Testosterone Esters in the Prepubertal and Pubertal Age Groups

Endocrinology Research and Practice, 2022
Long-acting intramuscular testosterone esters at various doses using various protocols are suggested for the treatment of micropenis and/or delayed puberty of childhood.
Zehra Aycan, Gönül Öcal, Merih Berberoğlu, Olcay Evliyaoğlu, Pelin Adıyaman   +4 more
doaj  

Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel, Aureliane Pierret, Edouard G. Mills, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Estimating thresholds for risk of cannabis use disorder using standard delta‐9‐tetrahydrocannabinol (THC) units

Addiction, EarlyView.
Abstract Background and aims Lower risk guidelines for safer levels of cannabis use could help to reduce the health burden posed by cannabis use disorder (CUD). We aimed to estimate risk thresholds for CUD based on delta‐9‐tetrahydrocannabinol (THC) consumption using standard THC units (1 unit = 5 mg THC).
Rachel Lees Thorne, Will Lawn, Kat Petrilli, Katie Trinci, Anya Borissova, Shelan Ofori, Claire Mokrysz, H. Valerie Curran, Lindsey A. Hines, Tom P. Freeman   +9 more
wiley   +1 more source

Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the developing male Wistar(Han) rat II: chronic dosing causes developmental delay [PDF]

, 2007
We have investigated whether fetal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes defects in the male reproductive system of the rat, using chronically exposed rats to ensure continuous exposure of the fetus. 5-6 week old rats were exposed
Bell, David Robert, Clode, Sally, Fan, MingQi, Fernandes, Alwyn, Foster, Paul M D, Jiang, tao, Loizou, George, MacNicoll, Alan, Miller, Brian G, Rose, Martin, Tran, Lang, White, Shaun   +11 more
core   +1 more source