Results 121 to 130 of about 31,437 (284)
Incidence of Delayed Puberty in Adolescents : A Population-Based Study in a County in Central Sweden
Introduction: Delayed puberty is defined as the absence of physical signs of puberty by the age of 14 years in boys and 13 years in girls. According to this definition, the prevalence of delayed puberty would be 2%, if the ages of pubertal onset were ...
Rodanaki, Maria, +2 more
core
ABSTRACT Hereditary angioedema (HAE) with C1 inhibitor deficiency is a rare disease characterized by unpredictable episodes of tissue swelling (angioedema), which, in most cases, occur first under the age of 18 years, and entail a significant burden of disease not only for the patients but also for their families.
Henriette Farkas +128 more
wiley +1 more source
The role of iron in normal and impaired testicular function
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer +2 more
wiley +1 more source
Algorithms for the Initial Management of Precocious or Delayed Female Puberty [PDF]
peer reviewedAn algorithmic approach is proposed for the initial management of disorders of female puberty: premature pubarche and precocious or delayed breast ...
LEBRETHON, Marie-Christine +1 more
core
Abstract Objective We aimed to investigate the association of a low serum testosterone concentration with the risk of abnormal glucose metabolism (i.e., prediabetes and type 2 diabetes) in men at a 15‐year follow‐up. Study population and methods In a population birth cohort, men with low testosterone (testosterone < 12.1 nmol/L, n = 136) and normal ...
Tuomisto A +7 more
wiley +1 more source
ABSTRACT Background Male hypogonadotropic hypogonadism typically presents with azoospermia and is one of the few causes of infertility amenable to a medical intervention. Gonadotropin therapy offers a chance to restore spermatogenesis and fertility in these individuals.
Manou Huijben +3 more
wiley +1 more source
Empty sella Syndrome as a Cause of Hypopituitarism Case study
Background:Empty sella syndrome is the radiological appearance of an enlarged or deformed sella turcica which is partially or completely filled with cerebrospinal fluid .In 20-50% of patients there may be endocrinologic dysfunction, pan hypopituitarism ...
Yousif Baha'addin Ahmed
doaj +2 more sources
Long-Term Health Outcomes of Delayed Puberty in Males : A Comprehensive Population-Based Study
Introduction: Delayed puberty in boys, defined as lack of pubertal onset by the age of 14 years, is often constitutional and self-limited. However, it can lead to feelings of sadness and anxiety.
Lennartsson, Otto, +5 more
core
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz +12 more
wiley +1 more source
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley +1 more source

