Results 101 to 110 of about 572,136 (283)

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source

Delayed puberty

BMJ, 1985
L H Zondek, T Zondek
openaire   +4 more sources

Macroglossia: An Uncommon Manifestation of Primary Hypothyroidism due to Hashimoto's Thyroiditis in a Teenage Child

Journal of the ASEAN Federation of Endocrine Societies, 2017
Thyroid disorders are prevalent in the paediatric population and untreated hypothyroidism leads to several adverse consequences like mental retardation, neurological impairment, short stature, delayed puberty and increased morbidity.
Manish Gutch, Annesh Bhattacharjee, Kumar Sukriti, Arpit Gupta, Rao Somendra Singh   +4 more
doaj  

Adaptation to Clean Intermittent Catheterization From Introduction Through Implementation: What Patients and Families Need to Know: A Position Document From the International Children's Continence Society (ICCS)

Neurourology and Urodynamics, EarlyView.
ABSTRACT Background Clean intermittent catheterization (CIC) plays a key role in the management of children whose neurological, anatomical, or functional conditions hinder complete or spontaneous bladder emptying. Its significance extends beyond clinical outcomes, influencing family relationships, psychosocial development, school experiences, and the ...
Anka J. Nieuwhof‐Leppink, Lillian C. Hayes, Joanna Clothier, Stuart B. Bauer   +3 more
wiley   +1 more source

Nutritional management, dietary intervention, and long‐term monitoring in pediatric Prader–Willi syndrome: A 3‐year case‐based clinical observation

Nutrition in Clinical Practice, EarlyView.
Abstract Nutritional management is fundamental in Prader–Willi syndrome (PWS), but longitudinal data from routine pediatric practice are limited. We describe a 3‐year nutritional follow‐up of a boy with PWS complicated by obesity, insulin resistance, dyslipidemia, hyperuricemia, and fatty liver.
Peipei Chen, Hui Pan, Wei Chen
wiley   +1 more source

From biological marker to clinical application: the role of anti-Müllerian hormone for delayed puberty and idiopathic non-obstructive azoospermia in males

Endocrine Connections
Anti-Müllerian hormone (AMH), a biomarker secreted by Sertoli cells in the testes, has emerged as a critical indicator of male reproductive function with significant clinical application potential.
Yuanyuan Zeng, Guicheng Zhao, Yi Zheng, Xiaohui Jiang   +3 more
doaj   +1 more source

Assessment of Oxidative Stress, Vitellogenin, and Human Health Risks Derived From Nile Tilapia Exposed to Metals and Metalloids in Southeastern Brazil

Environmental Toxicology, EarlyView.
ABSTRACT Urban coastal lagoons are highly vulnerable ecosystems increasingly affected by metal contamination, as well as multiple anthropogenic stressors. This study evaluated ecotoxicological and human health risks associated with chronic metal exposure in Nile tilapia (Oreochromis niloticus) from an anthropogenically impacted lagoon in southeastern ...
Julia Araújo Alves, Priscila M. O. Muniz Cunha, Shênia Patrícia Corrêa Novo, Lorena Oliveira Souza Soares, Tatiana Dillenburg Saint‐Pierre, Fábio Veríssimo Correia, André Luís de Sá Salomão, Rachel Ann Hauser‐Davis, Enrico Mendes Saggioro   +8 more
wiley   +1 more source

Use of the gonadotropin-releasing hormone agonist triptorelin in the diagnosis of delayed puberty in boys

, 1995
To differentiate gonadotropin deficiency from delayed puberty in teenage boys, 0.1 mg/m2 of triptorelin, a gonadotropin-releasing hormone agonist, was administered subcutaneously at 4 AM.
TATO', Luciano, ZAMBONI, Giorgio, ANTONIAZZI, Franco   +2 more
core   +1 more source

Juvenile and Pubertal Exposure to Polystyrene Nanoplastics Impairs Epididymal Structure and Sperm Quality in Mice

Environmental Toxicology, EarlyView.
ABSTRACT Nanoplastics (NPs) are emerging environmental contaminants capable of crossing biological barriers, accumulating in tissues, and disrupting physiological pathways. The male reproductive system is particularly vulnerable during the postnatal period, a developmental window characterized by intense testicular differentiation and epididymal ...
Gabriel Magalhães Oliveira Rigo, Nicoly Caixêta Gonçalves, Cristiana Livramento Oliveira Pinto, Patrícia Corona Lopes, Raul Silva Santarem, Juliana Reis Machado, Régia Caroline Peixoto Lira, Ana Paula Ramos, Marcos Vinicius da Silva, Hugo Felix Perini, Gláucia Eloisa Munhoz de Lion Siervo   +10 more
wiley   +1 more source

Effect of Propylparaben on In Vitro Maturation of Porcine Oocytes and Embryo Development

Environmental Toxicology, EarlyView.
ABSTRACT Parabens are synthetic chemicals that, due to their antibacterial and fungicidal effects, are widely used as preservatives in food, cosmetics, and personal care products, such as shampoos, hair conditioners, body creams, soaps, deodorants, makeup, wet wipes, lotions, female hygiene products, and vaginal lubricants. Several years ago, they were
Elivier Núñez‐Macías, Fahiel Casillas, Yenny Ramírez‐Jara, Eduardo Casas, Alma López, Adyeni Barajas‐Salinas, Jaime Barraza, Brenda Casado, Ivan Bahena‐Ocampo, Lizbeth Juárez‐Rojas, Miguel Betancourt   +10 more
wiley   +1 more source