Results 111 to 120 of about 31,437 (284)
Muscle &Nerve, EarlyView.ABSTRACT Introduction/Aim Optimizing Management of Endocrine Complications in Duchenne Muscular Dystrophy (OPTIMIZE DMD) is an international consortium of clinicians created to advance endocrine and bone clinical care in DMD. The aim of this study was to better understand current views and practices regarding investigation and management of growth and ...
Claire L. Wood +131 more
wiley +1 more source
, 2011 Definition 44Physiology of normal puberty 46Pubertal staging 48Timing of puberty 52Premature sexual maturation 53Central precocious puberty (CPP) (gonadotropin-dependent precocious puberty) 54Abnormal patterns of gonadotropin secretion 56Gonadotropin ...
Gary Butler, Jeremy Kirk
core +1 more source
Pediatric Investigation, EarlyView.Monogenic and syndromic obesity in children often arises from defects in the leptin–melanocortin pathway. Understanding these rare genetic causes not only clarifies mechanisms of appetite regulation but also enables precision therapies, offering hope beyond lifestyle interventions.
Hadel Khalil +2 more
wiley +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Urban coastal lagoons are highly vulnerable ecosystems increasingly affected by metal contamination, as well as multiple anthropogenic stressors. This study evaluated ecotoxicological and human health risks associated with chronic metal exposure in Nile tilapia (Oreochromis niloticus) from an anthropogenically impacted lagoon in southeastern ...
Julia Araújo Alves +8 more
wiley +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Nanoplastics (NPs) are emerging environmental contaminants capable of crossing biological barriers, accumulating in tissues, and disrupting physiological pathways. The male reproductive system is particularly vulnerable during the postnatal period, a developmental window characterized by intense testicular differentiation and epididymal ...
Gabriel Magalhães Oliveira Rigo +10 more
wiley +1 more source
Etiology of Delayed Puberty in the Institute for Endocrinology and Metabolism
, 2008 Objective:Delayed puberty is defined as lack of breast development after the age of 13 years in girls, and lack of testes enlargement after the age of 14 years in boys. Considering the importance of delayed puberty, the present study tries to analyze its
Rashad, Abbas, Rohani, Farzaneh
core +1 more source
Worldwide Burden of Hearing Loss Across Childhood and Adolescence, 1990–2021, and Projection to 2050
World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Objectives This article aims to analyze the trends in hearing loss (HL) prevalence and years lived with disability (YLDs) in children and adolescents from 1990 to 2021, and the corresponding health inequalities, decomposing causes, and future trends.
Jiao Zhang +8 more
wiley +1 more source
Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel +5 more
wiley +1 more source
Addiction, EarlyView.Abstract Background and aims Lower risk guidelines for safer levels of cannabis use could help to reduce the health burden posed by cannabis use disorder (CUD). We aimed to estimate risk thresholds for CUD based on delta‐9‐tetrahydrocannabinol (THC) consumption using standard THC units (1 unit = 5 mg THC).
Rachel Lees Thorne +9 more
wiley +1 more source