Results 111 to 120 of about 540,529 (281)

Delayed puberty

BMJ, 1985
L H Zondek, T Zondek
openaire   +3 more sources

New PMCT multi‐indicator ossification standards for age estimation of the knee in modern Australian and North American children

Journal of Forensic Sciences, EarlyView.
Abstract Skeletal age estimation is crucial to medicolegal work, aiding subadult identification, and living age assessments in legal contexts. This study aims to document the ontogeny of knee skeletal indicators on post‐mortem computed tomography (PMCT), and quantify interpopulation variation between modern American and Australian children.
Taliah Swart, Clair Alston‐Knox, Samantha K. Rowbotham, Soren Blau, Nicolene Lottering   +4 more
wiley   +1 more source

Reproductive Biology, Mating System, and Extended Natal Association in the Echolocating Dalou Mountains Tree Mouse (Typhlomys daloushanensis): Insights Into Sensory Adaptation and Life‐History Strategy

Integrative Zoology, EarlyView.
Typhlomys daloushanensis, a poorly known and unique echolocating rodent. Using a captive breeding colony, we quantify key reproductive parameters, including gestation length, litter size, interbirth interval, and development to maturity, and evaluate these in relation to mating system structure.
Juncheng Li, Tianyu Ren, Tian Tian, Chris Newman, Rui Yuan, Nan Wu, Christina D. Buesching, Youbing Zhou, Jinwei Wu   +8 more
wiley   +1 more source

Management of delayed puberty [PDF]

BMJ, 1985
openaire   +5 more sources

Estimating thresholds for risk of cannabis use disorder using standard delta‐9‐tetrahydrocannabinol (THC) units

Addiction, EarlyView.
Abstract Background and aims Lower risk guidelines for safer levels of cannabis use could help to reduce the health burden posed by cannabis use disorder (CUD). We aimed to estimate risk thresholds for CUD based on delta‐9‐tetrahydrocannabinol (THC) consumption using standard THC units (1 unit = 5 mg THC).
Rachel Lees Thorne, Will Lawn, Kat Petrilli, Katie Trinci, Anya Borissova, Shelan Ofori, Claire Mokrysz, H. Valerie Curran, Lindsey A. Hines, Tom P. Freeman   +9 more
wiley   +1 more source

Postcode‐Level Variation and Environmental Determinants of Respiratory Allergies in a Large German Cohort

Allergy, EarlyView.
Young children (0–9 years) and residents of urban areas appeared particularly vulnerable to respiratory allergy development and exacerbation. Incidence showed nonlinear associations with PM10, PM2.5, temperature, and alder/birch pollen, while DPMR showed similar patterns, except for NO2 and the interaction O3*NO2.
Trang Dao‐Siebel, Christoph Knote, Christoph Müller, Thilo Erbertseder, Elke Hertig, Roxana Halbleib, Evelyn Lamy   +6 more
wiley   +1 more source

Nasal Epithelial Immune Signatures Are Associated With Age‐Dependent Asthma Trajectories in Early Life

Allergy, EarlyView.
Nasal epithelial transcriptomics identified three cytokine‐associated epithelial immune programs linked to childhood asthma phenotypes. Age‐associated epithelial polarization shifted from IFN/type‐17‐associated toward type‐2‐associated programs after 3 years of age.
Constanze A. Jakwerth, Sabina Illi, Helen Charles, Madlen Oelsner, Amr A. Gabr, Ulrich M. Zissler, Anna Erb, Martin Feuerherd, Felix Drost, Maren Büttner, Benjamin Schubert, Nicole Maison, Jimmy Omony, Markus Weckmann, Ruth Grychtol, Anna‐Maria Dittrich, Svenja Foth, Chrysanthi Skevaki, Tobias Trojan, Silke van Koningsbruggen‐Rietschel, Gesine Hansen, Thomas Bahmer, Klaus F. Rabe, Folke Brinkmann, Matthias Volkmar Kopp, Ulrike Protzer, Adam M. Chaker, Bianca Schaub, Erika von Mutius, Carsten B. Schmidt‐Weber, the ALLIANCE Study Group as part of the German Center for Lung Research (DZL), Mira Bürk, Sybille Contento, Markus Ege, Kristina Gottschau, Silvia Gschwendtner, Alexander Hose, Lena Lagally, Michael Schloter, Lena Ullemeyer, Esther Zeitlmann, Mustafa Abdo, Heike Biller, Karoline I. Gaede, Clara Haug, Nikolas Jacobs, Anne‐Marie Kirsten, Inke R. König, Lea Kronziel, Gyde Nissen, Frauke Pedersen, Loana Pennerd, Isabell Ricklefs, Vera Veith, Henrik Watz, Marie Bickes, Mifflin‐Rae Calvero, David S. DeLuca, Svenja Gaedcke, Anika Habener, Christine Happle, Adan Chari Jirmo, Bin Liu, Lennart Riemann, Nicolaus Schwerk, Inga Jerrentrup, Harald Renz, Stefanie Weber, Miguel A. Alejandre Alcazar, Samira Blau, Ernst Rietschel, Jan‐Christoph Thomassen   +71 more
wiley   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Unraveling Delayed Puberty: A Rare Case of Congenital Hypogonadotropic Hypogonadism Masked by Celiac Disease and Plummer–Vinson Syndrome

Clinical Case Reports
Congenital hypogonadotropic hypogonadism (CHH) is a rare disorder that results in delayed puberty and infertility due to impaired secretion of gonadotropin‐releasing hormone (GnRH).
Osama Ahmad, Uzma Akbar, Fatima Sajjad, Muhammad Abdullah Ali, Umama Alam, Zaryab Bacha, Jibran Ikram, Malik W. Z. Khan   +7 more
doaj   +1 more source

Mesenchymal Stem Cells From a Klinefelter Syndrome Patient: Functional Characterization and Therapeutic Implications

Andrology, EarlyView.
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz, Wioletta Lech, Anna Figiel‐Dabrowska, Marta Kot, Magdalena Murzyn, Natalia Malawska, Barbara Pienkowska‐Grela, Zuzanna Sandowska‐Markiewicz, Iwona Ziolkowska‐Suchanek, Agnieszka Zimna, Tomasz Oldak, Natalia Rozwadowska, Anna Sarnowska   +12 more
wiley   +1 more source