Results 81 to 90 of about 540,529 (281)

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Fifteen-minute consultation: Delayed puberty in girls

open access: yes
Delayed puberty in girls most commonly presents as absent breast development by age 13 years and occurs less frequently than delayed puberty in boys.
Emily Morrow   +2 more
core   +1 more source

Development of a Machine Learning Algorithm for Differential Diagnosis Between Primary Immune Thrombocytopenia and Connective Tissue Disease‐Related Thrombocytopenia in Pediatric Patients

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Primary immune thrombocytopenia (ITP) and connective tissue disease‐related thrombocytopenia (CTD‐TP) share overlapping initial presentations in children, often leading to delayed diagnosis and suboptimal management. While existing literature focuses on therapeutic strategies, this study is the first to develop a machine learning (ML)‐based diagnostic ...
Furong Kang   +4 more
wiley   +1 more source

Sleep disturbance as a transdiagnostic marker of children's mental health difficulties: A network analysis of item‐level associations between different types of sleep problems and different behavioural and emotional symptoms

open access: yesJCPP Advances, EarlyView.
Abstract Background Sleep disturbances are widely considered to be a transdiagnostic feature of common behavioural and emotional difficulties in childhood, yet most studies treat sleep as a single construct. Where studies have explored specific sleep problems to psychopathology in children, these tend to only include behavioural or emotional ...
Alina A. Marinca   +4 more
wiley   +1 more source

Patterns of psychopathology and personal strengths among youth in psychiatric care

open access: yesJCPP Advances, EarlyView.
Abstract Background The American Academy of Pediatrics and the American Academy of Child and Adolescent Psychiatry have declared a National State of Emergency in Children's Mental Health, calling for improved approaches to address youth mental health.
Logan R. Cummings   +78 more
wiley   +1 more source

‘I don't know what is autism, what is normal teenage behaviour, and what is naughtiness’: Conceptualising child and adolescent to parent violence in the context of neurodevelopmental difference

open access: yesChildren &Society, EarlyView., 2023
Abstract This article presents findings from a UK‐based qualitative study that explored parents/carers experiences of child to parent violence (CPV) from their child who has a neurodevelopmental difference. The study used semi‐structured interviews with 15 mothers who were experiencing physical and psychological violence from their child, often on a ...
Amanda Holt
wiley   +1 more source

Association between the onset age of puberty and parental height.

open access: yesPLoS ONE, 2019
BACKGROUND:The onset age of physiological puberty is greatly variable. This variability has been attributed to environmental factors and to genetic factors although a very little is explained by genome-wide associations studies.
Yehuda Limony   +2 more
doaj   +1 more source

A 21-year-old Man with Delayed Puberty [PDF]

open access: yes, 2020
Delayed puberty is defined clinically by the absence or incomplete development of secondary sexual characteristics bounded by an age at which 95 percent of children of that sex and culture have initiated sexual maturation.
Hassanpour Akbar   +7 more
core  

Childhood adversity and psychotic‐like experiences in adolescence: Investigating a pathway via disrupted pubertal and grey matter development

open access: yesJCPP Advances, EarlyView.
Abstract Background Childhood adversity increases psychosis risk, but the biological mechanisms responsible remain elusive. A possible but underexplored pathway involves altered pubertal and grey matter (GM) development. Methods In youth from the Adolescent Brain Cognitive Development study (N = 3462), we investigated the effect of adversity at age 9 ...
Megan Thomas   +3 more
wiley   +1 more source

IGSF10 mutations dysregulate gonadotropin‐releasing hormone neuronal migration resulting in delayed puberty

open access: yesEMBO Molecular Medicine, 2016
Early or late pubertal onset affects up to 5% of adolescents and is associated with adverse health and psychosocial outcomes. Self‐limited delayed puberty (DP) segregates predominantly in an autosomal dominant pattern, but the underlying genetic ...
Sasha R Howard   +19 more
doaj   +1 more source

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