Results 71 to 80 of about 540,529 (281)

Alternate-day fasting delays pubertal development in normal-weight mice but prevents high-fat diet-induced obesity and precocious puberty

Nutrition & Diabetes
Background/Objectives Childhood obesity, particularly in girls, is linked to early puberty onset, heightening risks for adult-onset diseases. Addressing childhood obesity and precocious puberty is vital to mitigate societal burdens.
Rahim Ullah, Chuqing Xue, Senjie Wang, Zhewen Qin, Naveed Rauf, Shumin Zhan, Naimat Ullah Khan, Yi Shen, Yu-Dong Zhou, Junfen Fu   +9 more
doaj   +1 more source

Endocrine manifestations of celiac disease

Indian Journal of Endocrinology and Metabolism, 2012
Background: Celiac disease can have extra gastrointestinal tract (GIT) presentations, most of which are endocrine. The aim of this study was to present patients diagnosed to have celiac disease from an endocrine department and to study the prevalence of ...
R Philip, P P Patidar, S Saran, P Agarwal, TVS Arya, K K Gupta   +5 more
doaj   +1 more source

Hypogonadotrophic hypogonadism, delayed puberty and risk for neurodevelopmental disorders

, 2019
BACKGROUND: Hypogonadotropic hypogonadism (HH) is a rare disorder that manifests absent puberty and infertility. Genetic syndromes with hypogonadism, such as Klinefelter syndrome, are associated with an increased risk of neurodevelopmental disorders ...
Vide Ohlsson Gotby, Almqvist, Catarina,, Serlachius, Eva,, Henrik Larsson, Ohlsson Gotby, Vide,, Frisén, Louise,, Larsson, Henrik,, Catarina Almqvist, Paul Lichtenstein, Louise Frisén, Tammimies, Kristiina,, Eva Serlachius, Kristiina Tammimies, Lichtenstein, Paul,, Sven Bölte, Bölte, Sven,, Olle Söder, Söder, Olle,   +17 more
core   +1 more source

Treatment of delayed puberty and hypogonadism in girls [PDF]

, 1991
The therapeutic management of female delayed puberty depends more on the objectives than on the underlying cause. We will have to consider the development of sex characteristics, the occurrence of menarche and the promotion of growth.
Heinrichs, Claudine, Bourguignon, Jean-Pierre   +1 more
core   +1 more source

Epilepsy syndromes classification

Epilepsia Open, EarlyView.
Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell, Nicola Specchio, Rima Nabbout, Phillip L. Pearl, Kate Riney   +4 more
wiley   +1 more source

CRANIOPHARYNGIOMA: A CASE WITH DELAYED PUBERTY

Pakistan Armed Forces Medical Journal, 2011
Craniopharyngiomas are benign and aggressive epithelial neoplasms, comprising approximately 3% of all intracranial tumors1. These are the most common childhood tumor involving the hypothalamus and pituitary2. Endocrine disturbances may present in 80-90%
Syed Khawar Ali, Rizwan Hashim, Farooq Ahmad Khan   +2 more
doaj   +2 more sources

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

Attitudes toward sodium valproate use, withdrawal, and counseling in people of reproductive potential: A scoping review

Epilepsia Open, EarlyView.
Abstract Regulatory restrictions and evolving clinical guidelines have aimed to reduce sodium valproate use in people of reproductive potential over the past decade due to its teratogenic risk. While clinical evidence and policy responses are well established, stakeholder perspectives remain less explored.
Katherine Wang, Sarah Loveday, Monica S. Cooper, Emma Macdonald‐Laurs   +3 more
wiley   +1 more source

LXRα and PPARα Mediated Hepatic Lipid Metabolic Disruption Induced by the UV Filter EHMC in 2D and 3D HepaRG Cell Models

Food Safety and Health, EarlyView.
Dietary UV filter EHMC induces hepatic steatosis in HepaRG cells at noncytotoxic concentrations. Mechanistically, EHMC binds nuclear receptors (LXRα, PPARα), upregulating SREBP‐1 to accelerate fatty acid synthesis. These findings highlight the potential metabolic toxicity of widespread EHMC exposure through food sources.
Shanglin Yang, Na Li, Yingnan Han, Mei Ma   +3 more
wiley   +1 more source

Delayed and Precocious Puberty: Genetic Underpinnings and Treatments

, 2020
Delayed puberty may signify a common variation of normal development, or indicate the presence of a pathologic process. Constitutional delay of growth and puberty is a strongly familial type of developmental pattern and accounts for the vast majority of ...
Eugster, Erica A., Gohil, Anisha
core   +1 more source