Results 71 to 80 of about 2,220,873 (330)

Investigation of montelukast effect on rosuvastatin induced late puberty in rats

open access: yesJournal of Human Reproductive Sciences, 2022
Background: Puberty is a critical process for the development of sexual organs and reproductive ability. It is triggered and regulated by the hormones.
Tamadir Hamid Wadi Aledani   +3 more
doaj   +1 more source

Association of Prenatal Urinary Concentrations of Phthalates and Bisphenol A and Pubertal Timing in Boys and Girls. [PDF]

open access: yes, 2018
BackgroundAnimal studies suggest that phthalates and bisphenol A (BPA), endocrine-disrupting chemicals found in many consumer products, may impact the timing of puberty.ObjectivesWe aimed to determine the association of prenatal exposure to high ...
Berger, Kimberly   +9 more
core   +1 more source

Bone size and bone strength are increased in obese male adolescents [PDF]

open access: yes, 2013
Context: Controversy exists on the effect of obesity on bone development during puberty. Objective: Our objective was to determine differences in volumetric bone mineral density (vBMD) and bone geometry in male obese adolescents (ObAs) in overlap with ...
De Schepper, Jean   +11 more
core   +2 more sources

Descriptive Epidemiology From the Myhre Syndrome Foundation Registry: The Value of Self‐Reported Data

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome is an ultrarare genetic disease characterized by short stature, distinct craniofacial features, cardiovascular and respiratory fibrosis and stenosis, neurodevelopmental delays, autism, intellectual disability, and hearing loss. The natural history of Myhre syndrome is still not fully understood due to a small patient population ...
Mary K. Young   +6 more
wiley   +1 more source

Longitudinal Phenotypic Trajectories in GNAO1‐Related Disorders: Defining Disease Progression and Clinical Profiles

open access: yesAnnals of Neurology, EarlyView.
Objective Pathogenic variants in GNAO1 cause a spectrum of epilepsy, movement disorders, and developmental impairment. Clinical heterogeneity complicates prognosis and therapeutic development. We present the first longitudinal natural history study of GNAO1‐related disorders (GNAO1‐RD) to delineate phenotypic trajectories. Methods Sixty‐six individuals
Jana Domínguez‐Carral   +52 more
wiley   +1 more source

A Novel Homozygous Mutation of the Acid-Labile Subunit (IGFALS) Gene in a Male Adolescent

open access: yesJCRPE, 2019
Acid-labile subunit (ALS) forms ternary complexes with insulin like growth factor-1 (IGF-1) and IGF-binding protein-3 (IGFBP-3) and is essential for normal circulating IGF-1 levels.
Şükran Poyrazoğlu   +5 more
doaj   +1 more source

Testicular expression of the Lin28/let-7 system: hormonal regulation and changes during postnatal maturation and after manipulations of puberty [PDF]

open access: yes, 2015
[Abstract] The Lin28/let-7 system, which includes the RNA-binding proteins, Lin28a/Lin28b, and let-7 miRNAs, has emerged as putative regulator of puberty and male gametogenesis; yet, its expression pattern and regulation in postnatal testis remain ill ...
Cordido, Fernando   +8 more
core   +2 more sources

Beighton Scoring System Use in Generalized Joint Hypermobility Studies Has Greater Scientific Rigor Than Joint‐Specific or Arthroscopy Joint Hypermobility Studies

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To compare the scientific rigor of Beighton Scoring System (BSS) use in generalized joint hypermobility (JH) studies (healthy subject injury risk/rate, physiological or kinesiological function determination) and joint‐specific or arthroscopy JH studies; to identify the most commonly used BSS score thresholds; and to describe ways to improve BSS
John Nyland   +5 more
wiley   +1 more source

The onset of puberty in adolescents with type 1 diabetes mellitus in comparison to a group of non-diabetic teenagers in Erbil City: A cross-sectional comparative study

open access: yesZanco Journal of Medical Sciences
Background and objective: Puberty and type 1 diabetes (T1DM) have a complex relationship. This study aims to determine the prevalence of delayed puberty among a sample of type 1 diabetes adolescents and compare it to a non-diabetic group.
Ali Shakir Dauod   +2 more
doaj   +1 more source

Development of Replacement Heifers using Combinations of Three Forage Types and Feed Supplements (with or without Broiler Litter) [PDF]

open access: yes, 1997
The proper management of replacement heifers is an essential component of successful cow/calf operations. The level of management and nutrition applied to replacement heifers as calves and yearlings can impact their subsequent reproductive performance ...
Brown, A. H., Jr.   +4 more
core   +2 more sources

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