Results 51 to 60 of about 573,752 (297)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Using decision problems in public key cryptography [PDF]
There are several public key establishment protocols as well as complete public key cryptosystems based on allegedly hard problems from combinatorial (semi)group theory known by now.
Shpilrain, Vladimir, Zapata, Gabriel
core +3 more sources
Quantum asymmetric cryptography with symmetric keys
Based on quantum encryption, we present a new idea for quantum public-key cryptography (QPKC) and construct a whole theoretical framework of a QPKC system.
A. Kawachi +41 more
core +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
EthVault: A Secure and Resource‐Conscious FPGA‐Based Ethereum Cold Wallet
Cryptocurrency blockchain networks safeguard digital assets using cryptographic keys, with wallets playing a critical role in generating, storing, and managing these keys.
Joel Poncha Lemayian +3 more
doaj +1 more source
A New Class of Strongly Asymmetric PKA Algorithms: SAA-5
A new class of public key agreement (PKA) algorithms called strongly-asymmetric algorithms (SAA) was introduced in a previous paper by some of the present authors.
Luigi Accardi +3 more
doaj +1 more source
Cryptanalysis and improvement of an efficient certificateless signature scheme
In traditional digital signature schemes, certificates signed by a trusted party are required to ensure the authenticity of the public key. In Asiacrypt 2003, the concept of certificateless signature scheme was introduced.
Huang, Xinyi, Li, Jiguo, Mu, Yi, Wu, Wei
core +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source

