Results 31 to 40 of about 12,621 (207)
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Searchable Public Key Encryption Supporting Semantic Multi-Keywords Search
Searchable public key encryption (SPE) that supports multi-keywords search, allows data users to retrieve encrypted files of interest efficiently, and thus it has been intensively studied during recent years. However, most existing SPE solutions focus on
Yu Zhang, Yifan Wang, Yin Li
doaj +1 more source
Efficient All-or-Nothing Public Key Encryption With Authenticated Equality Test
Public key encryption with equality test (PKEET for short) is a new cryptographic primitive which allows a proxy to check whether two ciphertexts encrypted under different public keys are of the same plaintext.
Zhi-Yan Zhao, Peng Zeng
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
For efficiency improvement and public key size reduction, a new public key compression scheme is proposed for fully homomorphic encryption based on quadratic parameters with correction (QPC-PKC scheme).
Liquan Chen, Ming Lim, Zijuan Fan
doaj +1 more source
Pairing-Free for Public Key Encryption With Equality Test Scheme
The modular exponentiation has been proved better in terms of computational efficiency as compared to bilinear pairing. Therefore, discrete logarithm, a concept of modular exponentiation may be incorporated to present improved security schemes. With this
Huijun Zhu +3 more
doaj +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Multiple-Image Encryption Mechanism Based on Ghost Imaging and Public Key Cryptography
On the basis of ghost imaging, this paper proposes a multiple-image encryption scheme combining public key cryptography and Hadamard basis pattern. In the encryption system, a plurality of light paths are set, and the Hadamard basis patterns are used for
Leihong Zhang +3 more
doaj +1 more source
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source

