Results 61 to 70 of about 14,820,986 (315)

The Modified Dosages for Acute Malnutrition (MODAM) study: protocol for three integrated randomized controlled trials of novel approaches for the management of childhood wasting in Ethiopia

BMC Nutrition
Background Only a small percentage of children with severe and moderate acute malnutrition receive treatment due to resource limitations, relatively complex treatment protocols, persistent supply chain challenges, and limited early identification among ...
Indi Trehan, Yosef Beyene, Hiwot Darsene, Bailey S. Adams, Maria Wrabel, Getu Gizaw, Liya A. Legese, Bernardette Cichon, Stanley Chitekwe, Mesfin W. Shellemew, Masresha Tessema, Heather C. Stobaugh   +11 more
doaj   +1 more source

The HIV infection healthcare services continuity in the COVID-19 pandemic context: A mixed cross-sectional analysis of associated determinants in Senegal, 2020–2021

The Microbe
COVID-19 pandemic favoured concentration on its response to the detriment of routine services, such as people living with HIV (PLHIV) follow-up, hence the major services discontinuity risk. Thus, Senegalese National Epidemic Management Committee aimed to
Ibrahima Mamby Keita, Mamadou Makhtar Mbacke Leye, Ndeye Mareme Sougou, Boly Diop, Khaly Gueye, Amsatou Samb, Mansanou Fall, Moussa Ba, Bassirou Sarr, Mouhamadou Fallilou Seck, Mame Fatou Mbodj, Sophie Anna Diandy, Vincent Ahmed Gomis, Serigne Abdou Seck, Djibril Barry, Elhadji Mamadou Ndiaye   +15 more
doaj   +1 more source

Communities for Healthy Living (CHL) A Community-based Intervention to Prevent Obesity in Low-Income Preschool Children: Process Evaluation Protocol

Trials, 2020
Background Process evaluation can illuminate barriers and facilitators to intervention implementation as well as the drivers of intervention outcomes.
Jacob P. Beckerman-Hsu, Alyssa Aftosmes-Tobio, Adam Gavarkovs, Nicole Kitos, Roger Figueroa, Z. Begum Kalyoncu, Kindra Lansburg, Xinting Yu, Crystal Kazik, Adrienne Vigilante, Jessie Leonard, Merieka Torrico, Janine M. Jurkowski, Kirsten K. Davison   +13 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Kindness as a public health action

Communications Medicine
Abstract The current global mental health crisis needs action. Here we show, using empirical evidence of randomised controlled trials combined with Rose’s theoretical framework of preventive medicine and epidemiological principles, that the universal practice of kindness is a potentially effective grassroots public health promotion action ...
Tri-Long Nguyen, Ji-Young Lee
openaire   +4 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Collaborative writing as action research: A story in the making

, 2021
A small, transnational group of action researchers came into a collaborative writing venture as part of a broader research inquiry. The inquiry was looking into the role of action research publications in manifesting action research in the world.
Bessemer, Yedida, Vaartjes, Vicki, Goff, Susan, Austin, Diana, Hill, Geof, Orr, Liz   +5 more
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source