Results 81 to 90 of about 5,193,344 (310)

Finding the Voice of Public Health [PDF]

open access: yes, 2008
The Playbook for Action is a summary of the comments from the breakout discussions that followed each panel presentation at the 2008 Leaders to Leaders conference, organized to help leaders put their ideas into action.

core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Cost-effectiveness of decentralising acute malnutrition treatment with a standard or simplified treatment protocol: an economic evaluation in the region of Gao, Mali

open access: yesBMC Public Health
Background Acute malnutrition treatment coverage remains low worldwide, causing significant morbidity and mortality. Decentralisation of treatment to Community Health Worker (CHW) sites has shown to be an effective strategy to improve access and increase
Bernardette Cichon   +9 more
doaj   +1 more source

Preventing vaccine drop-outs: Geographic and system-level barriers to full immunization coverage among children in Uttar Pradesh, India

open access: yesVaccine: X
Objective: Global interventions on routine immunization aim to achieve at least 90 % immunization coverage of all vaccines as per national immunization schedules, aligning with the Immunization Agenda 2030.
Ravi Prakash   +11 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Psychosocial impacts of Baby Friendly Spaces for Rohingya refugee mothers in Bangladesh: A pragmatic cluster-randomized controlled trial

open access: yesCambridge Prisms: Global Mental Health
Background This study evaluated the effectiveness of Baby Friendly Spaces (BFS), a psychosocial support program for Rohingya refugee mothers of malnourished young children in Bangladesh.
Amanda J. Nguyen   +9 more
doaj   +1 more source

Local-level public goods and collective action [PDF]

open access: yes
According to the author, "Given the vital importance of public goods in providing basic services necessary for alleviating poverty and in managing the local natural resource base for sustainable development, this brief offers an approach to understanding
McCarthy, Nancy
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Multiple first-line therapeutic strategies to mitigate artemisinin resistance: cost analysis of a pilot study from a health system perspective in Kaya health district, Burkina Faso

open access: yesMalaria Journal
Background The emergence of artemisinin resistance in Africa is an increasingly evident threat to malaria control and elimination, and anticipatory measures are needed.
Rosemonde M. Guissou   +7 more
doaj   +1 more source

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