Results 71 to 80 of about 14,820,986 (315)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 2017 Action Learning finds its basis in experimental learning theory. For the staff at Western Public school Action Learning and experimental learning underpin their success of the use of Action Learning within their school.
Mehorter, Bronwyn Ruth
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BMC Health Services Research, 2018 Background General practice-based (GP) healthcare data have promise, when systematically collected, to support estimating local rates of chronic obstructive pulmonary disease (COPD) and asthma, variations in burden of disease, risk factors and comorbid ...
T. Niyonsenga +4 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Researching resilience in action: Matters of action research as ‘matters of care’
, 2022 This paper traces my Action Research (AR) journey and suggests a care perspective to AR. In my research that investigated the idea of resilience in disaster recovery, I engaged in a five-year collaborative inquiry of what it means to do resilience with a
Mikami, Akina
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
ALARA-BALT Australasian Action Learning, Action Research Conference 2020
, 2019 Announcement of ALARA-BALT Australasian Action Learning, Action Research Conference 2020 in Launceston, Tasmania on 8-10 November ...
Bradley, Colin
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Action learning, action research: Towards greater collaboration amongst networks
, 2018 Recent conversations with a variety of action learning and action research practitioners around the world have identified a growing desire for collaboration between networks.
Bradley, Colin
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Jack the lion – the making of a film about action research as action research
, 2020 In the pages that follow, it will be argued that the process of action research and the production of a documentary film are structurally comparable. Based on this assumption, this text tells the story of the making of a film on action research.
Har-Gil, Amir, Rauch, Franz
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