Results 101 to 110 of about 7,659,798 (344)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

A human resource management review on public management and public administration research: stop right there…before we go any further…

open access: yes, 2019
This overview paper focuses on the increased popularity of human resource management (HRM) in public management and public administration research. This is reflected in empirical articles published in scientific journals linked to HRM, public management ...
Paul Boselie   +2 more
semanticscholar   +1 more source

“Alternative for Germany” against German trade unions: A political “right hook”

open access: yesRUDN Journal of Public Administration
The study examines the problems of German trade unions related to the ongoing confrontation with the young party of the right-wing spectrum “Alternative for Germany” for several years.
Oleg E. Grishin, Alexander V. Kanushkin
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

The influence of non-political organizations on the activities of formalized political institutions in contemporary Japan

open access: yesRUDN Journal of Public Administration
The purpose of the research is to examine the mechanisms of influence of the South Korean Christian nationalist organization “Unification Church”2 in Japan. Particular attention is paid to its influence on the socio-political aspects of internal Japanese
Alexandra S. Roslyakova   +1 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

The use of blockchain technology for preserving cultural heritage and its impact on political processes

open access: yesRUDN Journal of Public Administration
One of the pressing issues in the modern world is the problem of trust in authority. Cultural heritage and the challenges associated with its acknowledgment and preservation often directly influence political processes both within countries and in ...
Denis A. Gromyko
doaj   +1 more source

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