BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach +11 more
wiley +1 more source
Mediating effect of job crafting dimensions on influence of burnout at self-efficacy and performance: revisiting health-impairment process of JD-R theory in public administration. [PDF]
Front Psychol, 2023 Martínez-Díaz A +5 more
europepmc +1 more source
Excess Land Law on the Kern?: A Study of Law and Administration of Public Principle vs. Private Interest [PDF]
, 1958 Paul S. Taylor
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The cervical spinal cord (cSC) is highly relevant to clinical dysfunction in multiple sclerosis (MS) but remains understudied using quantitative magnetic resonance imaging (MRI). We assessed magnetization transfer ratio (MTR), a semi‐quantitative MRI measure sensitive to MS‐related tissue microstructural changes, in the cSC and its ...
Lisa Eunyoung Lee +26 more
wiley +1 more source
Career management perspective in public administration [PDF]
An innovative public organization must be capable to access, internalize and implement the newest forms of knowledge and capitalize efficiently and effectively the potential of human resources available to it. Economic, political, social, administrative,
Camelia-Olivia ILIES
core
Improving Public Administration Performance through Electronic Government Applications [PDF]
, 2009 Electronic Government applications have been the focus of hundreds of local and national government administrations all over the world during the past decade.
Dastbaz, M, Jahankhani, H, Pimenidis, E
core
In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock +8 more
wiley +1 more source
Public administration role in infrastructure development [PDF]
The infrastructure (transport) is essential for the economic development of a region. If we are taking into consideration the tourism industry and other tourist activities, the importance of the infrastructure is higher, due to the fact that the ...
Grigorescu, Adriana
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To compare the effectiveness of high‐efficacy treatments (HET) and low‐efficacy treatments (LET) in NMOSD patients with anti‐aquaporin‐4 antibodies (AQP4‐ab). Methods In this multi‐center study, we analyzed 183 AQP4‐ab seropositive NMOSD patients who received immunosuppressive treatments (IST).
Xiang Li +10 more
wiley +1 more source
The Public Defender; A Necessary Factor in the Administration of Justice
, 1917 Robert H. Gault, Mayer C. Goldman
openalex +3 more sources