Results 101 to 110 of about 2,567,640 (311)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

User satisfaction with health services and healthcare delivery in Cape Verde

BMC Health Services Research
Background The evaluation of health services and care is an important tool to define health policies. This study aimed at assessing user satisfaction with healthcare services, provided by public and private health facilities in Cape Verde.
Maria da Luz Mendonça, Maria de Fátima Carvalho Alves, Janice Soares, Sónia Santos, Maria Natalina Silva, Edna Duarte Lopes, Jailson Jesus Martins, Jessica Ramos, Pedro Lopes Ferreira   +8 more
doaj   +1 more source

Personalized Genetic Testing and Norovirus Susceptibility

Canadian Journal of Infectious Diseases and Medical Microbiology, 2014
BACKGROUND: The availability of direct-to-consumer personalized genetic testing has enabled the public to access and interpret their own genetic information.
Natalie Prystajecky, Fiona SL Brinkman, Brian Auk, Judith L Isaac-Renton, Patrick Tang   +4 more
doaj   +1 more source

Control Rights in Complex Partnerships [PDF]

This paper develops a theory of the allocation of authority between two players who are in a “complex” partnership, that is, a partnership which produces impure public goods.
Francesconi, Marco, Muthoo, Abhinay
core  

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Predicting patient risk of leaving without being seen using machine learning: a retrospective study in a single overcrowded emergency department

BMC Emergency Medicine
Emergency department (ED) overcrowding has become a critical issue in hospital management, leading to increased patient wait times and higher rates of individuals leaving without being seen (LWBS). This study aims to identify key factors influencing LWBS
Arianna Scala, Teresa Angela Trunfio, Massimo Majolo, Michelangelo Chiacchio, Giuseppe Russo, Paolo Montuori, Giovanni Improta   +6 more
doaj   +1 more source

Effectiveness of a mRNA Vaccine Booster Dose Against COVID-19 Among Oregon Healthcare Personnel, January 2021-June 2023

Antimicrobial Stewardship & Healthcare Epidemiology
Background: The prioritization of U.S. health care personnel (HCP) for early receipt of messenger RNA (mRNA) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) allowed for the evaluation of the effectiveness of these vaccines ...
Madysen Schreiber, Eric Hall, Valerie Ocampo, Alexia Zhang, Angela Dusko   +4 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Qualitative study investigating the health needs of school-aged children and adolescents in Dubai

BMJ Open
Background Children’s health has been linked with morbidities such as cardiovascular events, type 2 diabetes and obesity in adulthood. Further efforts are needed to understand the current and emerging challenges due to the potential changes in the social
Ali Muneer Alrahma, Sana Easa Belal, Fatima Hassan Mohamed Koko, Kadhim Alabady   +3 more
doaj   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source