Results 121 to 130 of about 2,587,050 (312)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Public Authorities in Underdeveloped Countries

Law and Contemporary Problems, 1961
I. Enterprise and Development The non-communist underdeveloped countries provide an extraordinarily rich but as yet poorly-exploited field for the comparative study of public enterprise. It is not that they have shown any special capacity for institutional invention; on the contrary, the forms of public enterprise they have adopted are invariably ...
openaire   +2 more sources

Nesmeyanova S.E. Levels (centers) of public authority: modern interpretation of theory and practice

Правоприменение
The subject of the study is the legal relations arising from the public authority’s organization and its levels’ interaction after the constitutional reform of 2020. The organized interaction of the public authority levels determines the effectiveness of
A. V. Bleshchik, A. G. Kalinina, S. E. Nesmeyanova   +2 more
doaj   +1 more source

Establishment of Charter Schools in the Commonwealth of Virginia [PDF]

, 2016
Virginia is facing significant challenges related to public education such as decreased funding for public education, decreased teacher salaries, and overcrowded classrooms.
Epps, Shermese, Grace E. Harris Leadership Institute, Virginia Commonwealth University, Pegram, Germika, Reed, Edward, Sampe, Brenda, Warren, Courtney   +5 more
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

TO THE AUTHORS OF PUBLICATIONS

Российский кардиологический журнал, 2001
To the authors of publications.
openaire   +1 more source

Revealing Turkey’s Public Debt Burden: A Transparent Payments Approach [PDF]

We postulate a new method of identifying debt which we call Debt Burden (DB). We claim that DB reveals the true debt obligations of the fiscal authority. It is more accurate and transparent.
Can Erbil, Ertunc Alioglu, Ferhan Salman
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Masculinity as Governance: police, public service and the embodiment of authority, c. 1700-1850

, 2007
About the book: Public Men offers an introduction to an exciting new field: the history of masculinities in the political domain and will be essential reading for students and specialists alike with interests in gender or political culture.
D Taylor, E Wingate, EA Reynolds, Henry, J Burgh, J Hanway, J Ritson, JGA Pocock, M Young, MCRL, MCRL, MJ Braddick, ML McCormack, N Tadmor, P Colquhoun, P King, PN Miller, R Gardiner, S Welch, Sir F Bacon, W Blizzard, W Miller, W Sheppard   +22 more
core   +1 more source