Results 101 to 110 of about 2,587,050 (312)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

General Points of the Public Administration in Romania [PDF]

Ovidius University Annals: Economic Sciences Series, 2017
The present study presents some points of view about public administration. It also contains my arguments concerning general characteristics of the public administration. It.
Tincescu Ana-Maria
doaj  

Control Rights in Complex Partnerships [PDF]

This paper develops a theory of the allocation of authority between two players who are in a “complex” partnership, that is, a partnership which produces impure public goods.
Francesconi, Marco, Muthoo, Abhinay
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

The Improvement of Coordination of Public Authority and Local Authority in Moscow

RUDN Journal of Political Science, 2008
In the article is analyzed the effectiveness of local self-management in Russia. The author ties the level of effectiveness of self-management with coordination of public authority and the bodies of municipal self-management.
V S Bautdinova
doaj  

The first possible case of airport Zika virus infection in the EU/EEA

Travel Medicine and Infectious Disease
Since 2019, when the first autochthonous cases of ZIKV disease were observed in EU/EEA countries, no other locally acquired ZIKV disease cases have been reported in EU/EEA.Our case of ZIKV disease in 2024 had a history of flying from Slovakia to Italy ...
Jana Kerlik, Ján Hockicko, Mária Avdičová, Monika Musilová, Veronika Tarkovská, Elena Tichá, Hana Zelená   +6 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

User satisfaction with health services and healthcare delivery in Cape Verde

BMC Health Services Research
Background The evaluation of health services and care is an important tool to define health policies. This study aimed at assessing user satisfaction with healthcare services, provided by public and private health facilities in Cape Verde.
Maria da Luz Mendonça, Maria de Fátima Carvalho Alves, Janice Soares, Sónia Santos, Maria Natalina Silva, Edna Duarte Lopes, Jailson Jesus Martins, Jessica Ramos, Pedro Lopes Ferreira   +8 more
doaj   +1 more source

The Influence of Altitude, Urbanization, and Local Vaccination Centers on Vaccine Uptake within an Italian Health District: An Analysis of 15,000 Individuals Eligible for Vaccination

Vaccines
In Italy, free vaccinations for Herpes Zoster (HZ), pneumococcal (PCV), and influenza (FLU) are recommended each year for individuals turning 65. Despite this, achieving optimal vaccination coverage remains challenging. This study assesses coverage rates
Andrea Ceccarelli, Giorgia Soro, Chiara Reali, Emilia Biguzzi, Roberta Farneti, Valeria Frassineti, Raffaella Angelini, Gian Luigi Belloli, Davide Gori, Marco Montalti   +9 more
doaj   +1 more source

Moving Along the Learning Curve: From Values to Public Judgment: Citizen Dialogues on K-12 Education Reform [PDF]

, 2008
Based on dialogues with California's public, policy makers, and other stakeholders, assesses the public's priorities for K-12 reform and support for giving districts more authority and resources to meet state standards.
Heidi Gantwerk, Isabella Furth, Steven A. Rosell   +2 more
core