Results 71 to 80 of about 2,567,640 (311)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Enhancing public accountability in a city authority [PDF]
Journal of Work-Applied ManagementPurpose – This paper seeks to provide a multi-theoretical explanation of the living practice of a public entity found in Uganda, an African developing country, which successfully enhanced public accountability. Design/methodology/approach – A qualitative
Christopher Neil Makanga +5 more
doaj +1 more source
INDEPENDENCE OF PUBLIC PROCUREMENT AUTHORITY [PDF]
International Scientific Conference EMAN – Economics & Management: How to Cope with Disrupted Times, 2019 Nowadays, many countries suffer from loss of confidence of their citizens. Huge protests are spread throughout many states even in the EU. The time has come to analyse the principles of good governance in order to make states trustworthy organisations again.
openaire +1 more source
Looking for Trickledown Under the Peace Bridge: A Critique of the Public Bridge Authority\u27s Economic Impact Claims [PDF]
, 2011 The Public Bridge Authority’s economic impact analysis, presented in its environmental impact statement for the Peace Bridge Expansion Project, offers a grossly exaggerated impression of the project’s benefits.
core +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Journal of Architecture, Art & Humanistic Science, 2020 The early Kuwaitis lived in simple houses and did not know luxury or modern buildings until after the emergence of oil and the beginning of the urban renaissance in the fifties.
Haya Ahmed Ali, Diana Kamel Yousif
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Public health reasoning: a logical view of trust [PDF]
, 2014 The public has a pact with the experts who deliver public health. That pact can be characterized as a relationship of trust in which the public trusts health experts to act in its best interests in return for its adherence to recommendations and other ...
Cummings, L
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Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Drinking can harm a foetus, but court finds girl born with disorder wasn’t victim of crime [PDF]
, 2014 This is a paper about the Court of Appeal judgement in CP (A Child) v Criminal Injuries Compensation Authority [2014] EWCA Civ 1554. The story behind the case has stirred up considerable public and media debate.
Wale, Jeffrey
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