Results 111 to 120 of about 1,286,583 (307)
The New Politics of Judicial Elections 2009-10 [PDF]
, 2011 Examines trends in the impact of special interest groups' spending on judicial elections, TV advertising, and implications such as threats of impeachment for unpopular decisions, attacks on merit selection systems, and danger to public election ...
Adam Skaggs +3 more
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FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Sustainability of national debt in Europe: why it matters in the EMU and how it is assessed [PDF]
There are at least two reasons why sustainability of public debt is an issue of increasing importance. First, public choice considerations show the danger of an excessive use of deficit finance in a democracy.
Heinemann, Friedrich
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Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Some Issues on Reforming the Legislation on Administrative Offences
Сибирское юридическое обозрение, 2020 Some problems of modern administrative-tort law are considered. Attention is focused on a number of key problems of the current legislation on administrative offenses and on some specific proposals for its amendment.
S. I. Koryts, I. B. Bokova
doaj
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
"The Return of Big Government--Policy Advice for President Obama" [PDF]
In the current global financial crisis, economists and policymakers have reembraced Big Government as a means of preventing the reoccurrence of a debt-deflation depression.
L. Randall Wray
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
On Some Problems of Criminal Law Regulation of the Situation Change in Russia, Mongolia and China
Vestnik Omskoj Ûridičeskoj Akademii, 2013 The article deals with the analysis of the criminal law regulations in the Russian Federation, Mongolia, specifying the cause for release from criminal responsibility and punishment in consequence of some situation changes.
Kuznetsov A. V., Sun Yingchun
doaj
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source