Results 121 to 130 of about 5,906,880 (345)

Sustaining Public Engagement: Embedded Deliberation in Local Communities [PDF]

open access: yes, 2009
Describes nine communities using organized deliberation to consider public issues over several years and their accomplishments and analyzes how public deliberation addresses deficits in local democratic governance.
Archon Fung, Elena Fagotto
core  

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

open access: yesAdvanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu   +14 more
wiley   +1 more source

Government Deficits in the European Union: An Analysis of Entry and Exit Dynamics [PDF]

open access: yes
The extent of government deficits and debt has been one of the most debated issues in recent years. However, much less has been contributed about their dynamics.
Ali Bayar, Bram Smeets
core  

Government budget deficits in large open economies [PDF]

open access: yes, 2011
Large and growing levels of public debt in the United States, United Kingdom, Japan and the Euro Area raise new interest in the cross-country effects of a large open economy's deficits.
Buiter, W., Sibert, Anne
core  

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

open access: yesAdvanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren   +9 more
wiley   +1 more source

Inflation divergence and public deficits in a monetary union [PDF]

open access: yes
We reconsider the link between domestic public debts and average and domestic inflation rates in a monetary union, using a modified version of a model by Beetsma and Vermeylen (2002).
Jacques Le Cacheux, Jerome Creel
core  

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang   +18 more
wiley   +1 more source

Public expenditure and deficit in Spain (1958-2014)

open access: yesSemestre Económico, 2016
The objective of this study is to analyze a reduced model of the determinants of public spending growth from a demand side perspective. The model is based on the Buchanan and Wagner hypothesis but incorporates several other variables considered as determinants of public spending growth as well.
openaire   +3 more sources

Whither Public Interest: The Case of Greece's Public Finances [PDF]

open access: yes
During the last three decades there has been an almost continuous undermining of the public interest by private interests operating either outside or inside Greek public administration.
Christos Tsitsikas, Thomas Moutos
core  

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

open access: yesAdvanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao   +16 more
wiley   +1 more source

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