Results 81 to 90 of about 13,145,419 (304)

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Public Employment Services : Functions and Innovations

, 2003
Public Employment Services (PES) in industrialized countries have traditionally provided job-brokering services - arranging for jobseekers to obtain jobs and employers to fill vacancies. Increasingly, they
Dar, Amit
core   +1 more source

DIEZ ELEMENTOS CLAVE SOBRE LA GESTIÓN DE LA TEMPORALIDAD EN LA ADMINISTRACIÓN PÚBLICA TRAS LA FINALIZACIÓN DE LOS PROCESOS DE ESTABILIZACIÓN. ¿UN NUEVO PARADIGMA A PARTIR DE 2025?

Revista Vasca de Gestión de Personas y Organizaciones Públicas
This paper analyses, by means of ten elements that the author considers fundamental, how to cope with the management of temporality in public employment from 2025 onwards, after the end of the stabilization processes of temporary employment that started ...
XAVIER BOLTAINA BOSCH
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Differences in patient-reported outcomes across multimorbidity profiles in primary care: evidence from the first cycle of the OECD Patient Reported Indicator Surveys (PaRIS)

BMC Primary Care
Background Multimorbidity is a growing challenge for healthcare systems worldwide, yet policymakers and healthcare professionals often lack evidence on how distinct multimorbidity profiles (capturing co-occurrence of chronic conditions) relate to patient-
Candan Kendir, Nicolas Larrain, Michael van den Berg, Frederico Guanais, Niek Klazinga, Dionne Kringos, Mieke Rijken, Jose M Valderas   +7 more
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Employment Issues in Australian Public Sector Call Centres: Differences and Similarities with the Private Sector [PDF]

, 2005
Call centre development has been extensive and ongoing across the industrial world. These developments have resulted from an ongoing process of consolidation and restructuring ofservice work that has been facilitated by the continuing application of ...
Connell, JA, Burgess, J, Hannif, ZN
core  

Relational continuity, care coordination, and experience of person-centred care in primary care of people living with chronic conditions: a secondary, cross-sectional analysis of OECD PaRIS data

The Lancet Primary Care
Summary: Background: Relational continuity and care coordination are regarded as core functions of high-quality primary care, particularly for people with chronic conditions.
Ángel González de la Fuente, MD, Oscar Brito-Fernandes, PhD, Luke N Allen, PhD, Nicolás Larraín, PhD, Candan Kendir, MD, Frederico Guanais, PhD, Dionne Kringos, Prof, Michael van den Berg, PhD   +7 more
doaj   +1 more source