Results 61 to 70 of about 446,913 (314)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
International Review of Performance Management Systems in Public Employment Services
, 2010 This report presents the findings from a literature review which explores how other Public Employment Services (PES) across Europe use performance measurement in support of their organisational objectives in order that Jobcentre Plus can learn from this ...
Mitchell, B +5 more
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Desafíos pendientes para la definitiva implantación de la evaluación del desempeño
Revista Vasca de Administración Pública, 2017 It has been a decade since the Basic Statute of the Public Employee was passed without job evaluation, one of its most important bets to modernize Administration and public employment, has been implemented, nor the necessary foundations for its later ...
Pedro Padilla Ruiz
doaj +1 more source
The value of comparative research in major day surgery
Gaceta Sanitaria, 2018 Objective: To measure time trends in major day surgery rates according to hospital ownership and other hospital characteristics among the providers of the public healthcare network of Catalonia, Spain.
Alba Llop-Gironés +4 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Keynesian hospitals? Public employment and political pressure [PDF]
This paper uses an unusual administrative dataset covering the universe of French hospitals to consider hospital employment: this is consistently higher in public hospitals than in Not-For-Profit or private hospitals, even controlling for many measures ...
Andrew E. Clark, Carine Milcent
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Working to Reduce Poverty: A National Subsidized Employment Proposal
RSF: The Russell Sage Foundation Journal of the Social Sciences, 2018 Subsidized employment programs that increase labor supply and demand are a proven, underutilized strategy for reducing poverty in the short and long term.
Indivar Dutta-Gupta +4 more
doaj +1 more source
Public Employment Services : Functions and Innovations
, 2003 Public Employment Services (PES) in industrialized countries have traditionally provided job-brokering services - arranging for jobseekers to obtain jobs and employers to fill vacancies. Increasingly, they
Dar, Amit
core +1 more source