Results 141 to 150 of about 15,629,087 (290)

The Paradox of Progress: Genetic Counselling in a South African Context and the Challenges of Workforce Retention. [PDF]

Mol Genet Genomic Med
Schnell S, Fourie K, Gilfillan E, Rossouw B, Shingwenyana B, Thom J, Araujo M.   +6 more
europepmc   +1 more source

TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma

Advanced Science, EarlyView.
TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin, Cheung Kwan Yeung, Ye Yi, Dejin Zheng, Miaoman Ye, Chi‐Chong Chio, Jinjie Wu, Siyi Fu, Chu‐Xia Deng, Ren‐He Xu   +9 more
wiley   +1 more source

What a performance: performance related pay in the public services. [PDF]

Linking pay to performance is something employers increasingly seek to achieve. This was once seen as an objective which could only be met in the private sector. That is no longer true.
French, Stephen, Marsden, David
core  

"Work does change lives": a qualitative study exploring employment specialists' perspectives on assisting youth through supported employment in rural Canada. [PDF]

Int J Public Health
Warren C, McCulloch K, Su J, Wenger M, Barbic S.   +4 more
europepmc   +1 more source

Towards a Compositional Framework for Describing Human Phenotypes

Advanced Science, EarlyView.
The Phenotype Assembly Method (PhenoAM) decomposes phenotype variables into measurable Features and typed Qualifiers, enabling standardized, machine‐readable Phenome Data Elements (PhenoDEs) that preserve measurement context. Applied in the International Human Phenome Project (IHPP), the framework yields 58 371 PhenoDEs and supports component‐level ...
Wanting Hu, Yunchao Ling, Xinyue Hu, Wei Chen, Rong Zhou, Xinhao Zhuang, Yanfeng Jiang, Jialu Zhao, Xingdong Chen, Jingchun Luo, Li Jin, Guoqing Zhang   +11 more
wiley   +1 more source

The Role and Functioning of Public-Interest Legal Organizations in the Enforcement of the Employment Laws [PDF]

Many laws create important rights for today's employees, but the availability of legal representation for employees seeking to enforce those rights is uncertain.
Christine Jolls
core  

Implementing individual placement and support in autistic and other intellectually and developmentally disabled adults: lessons learned in California. [PDF]

Int J Public Health
Solomon M, Yon-Hernández JA, Smith MM, Zheng M, Llorente C, Downing A, Ruder S, Stahmer AC, McGurk SR.   +8 more
europepmc   +1 more source

A 3D‐Printed SFE‐Graded Alloy Mitigates Cryogenic Discontinuous Plastic Flow and Hydrogen Embrittlement

Advanced Science, EarlyView.
A novel strategy features gradient composition and stacking fault energy‐tuned (CoCrMn)100‐2xFexNix fabricated via in situ alloying additive manufacturing. This design circumvents cryogenic discontinuous plastic flow and hydrogen embrittlement of metallic materials under quasi‐static loading and hydrogen‐rich environment relevant to lunar polar ...
Renhao Wu, Ao Geng, Peihao Geng, Hyojin Park, Eun Seong Kim, Sang‐Ho Oh, Stephan Schönecker, Xiaoqing Li, Tianlong Zhang, Shuhui Li, Byeong‐Joo Lee, Hyoung Seop Kim   +11 more
wiley   +1 more source

Cross‐scale Material‐Structure Synergy for 2D Metamaterials: Toward Customizable Intelligent Electromagnetic Manipulation in Multiphysics Fields

Advanced Science, EarlyView.
Recent advances in metasurface‐enabled low‐observable technologies are reviewed from the perspective of cross‐scale material–structure synergy. Electromagnetic, thermal, optical, and acoustic stealth are highlighted together with dynamic tuning, programmable coding, data‐driven inverse design, artificial intelligence, multispectral compatibility, and ...
Shuhao Wang, Xing Yang, Liping Liu, Yang Peng, Yangyang Wang, Hualiang Lv   +5 more
wiley   +1 more source

What is the effectiveness of services and interventions for Armed Forces transitioning to veteran status, and what opportunities are there for improvement: a scoping review of health-related evidence. [PDF]

BMJ Open
Armitage JM, Robinson S, Bowater J, Melendez-Torres GJ, Barnish MS.   +4 more
europepmc   +1 more source