Results 101 to 110 of about 12,141,356 (259)

Coixenolide Enhances Antitumor Immunity of Cytotoxic CD8+ T Cells by Inhibiting S100A8/A9‐CD36 Axis in Obesity‐Associated Pancreatic Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen   +20 more
wiley   +1 more source

Attomolar Detection of HIV‐1 With Label‐Free RCA‐rCRISPR on Smartphone

open access: yesAdvanced Science, EarlyView.
A new diagnostic strategy integrating rolling circle amplification (RCA) with a plasmid reporter–based ratiometric CRISPR (rCRISPR) system was developed to detect unfragmented HIV genomes with single‐digit attomolar sensitivity. The method quantifies targets using the plasmid relaxation ratio and employs a smartphone‐based mini‐gel device to enable ...
Noor Mohammad   +12 more
wiley   +1 more source

An Adipocyte MKK3–p38β Axis Preserves Insulin Responsiveness in Mice and Is Reciprocally Altered in Human Obesity

open access: yesAdvanced Science, EarlyView.
The adipocyte MKK3–p38β axis emerges as an adaptive stress‐response pathway during obesity. Human visceral adipose tissue analyses, adipocyte‐specific mouse models, and primary adipocytes show that the MKK3–p38β axis supports insulin responsiveness by restraining p70S6K‐dependent inhibitory IRS1 feedback and preserving AKT–GLUT4 signaling. This pathway
Edgar Bernardo   +20 more
wiley   +1 more source

GOVERNMENT REVENUES AND EXPENDITURES IN GUINEA-BISSAU: CAUSALITY AND COINTEGRATION [PDF]

open access: yes
The paper establishes empirically the temporal causality and long run relationship between government expenditures and government revenues for the case of Guinea-Bissau - a low income country under stress (LICUS) in Africa.
Francisco G. Carneiro   +2 more
core  

PUBLIC EXPENDITURES EVOLUTION. POSITIVE OR NEGATIVE ASPECTS? [PDF]

open access: yesStrategii Manageriale, 2014
This article analyzes the situation of public spending and the transformations that occurred in state budgets over the past ten years in Romania. Data are collected from eurostat, state budgets laws and corrections occurred.
Mihai-Bogdan, PETRIȘOR
doaj  

Phase Diagrams and Piezoelectric Properties of Wurtzite Al1−x−yScxGdyN Heterostructural Alloys

open access: yesAdvanced Science, EarlyView.
This study demonstrates ferroelectricity and piezoelectric properties improvement of quaternary wurtzite Al1−x−yScxGdyN${\rm Al}_{1-x-y}{\rm Sc}_x{\rm Gd}_y{\rm N}$ films, guided by density functional theory calculations. Wurtzite Al1−x−yScxGdyN${\rm Al}_{1-x-y}{\rm Sc}_x{\rm Gd}_y{\rm N}$ films have a high optical bandgap, enhanced piezoelectric ...
Julia L. Martin   +11 more
wiley   +1 more source

Statistics on Public Expenditures for Economic Development (SPEED): 2019 Global Food Policy Report Table 2

open access: yes, 2018
The Statistics on Public Expenditures for Economic Development (SPEED) database is a resource of the International Food Policy Research Institute (IFPRI) that contains information on agricultural and other sectoral public expenditures in 147 countries ...
International Food Policy Research Institute (IFPRI)
core   +1 more source

PUBLIC EXPENDITURES POLITICS ON A NATIONAL LEVEL [PDF]

open access: yesAnnals of the University of Petrosani: Economics, 2013
The development level of a society is closely related to the development state of its individuals. Ensuring a high level of welfare for individuals is done through public politics.
ANA-PETRINA PĂUN, PETRE BREZEANU
doaj  

Political determinants of social expenditures in Greece: an empirical analysis

open access: yesPublic Sector Economics, 2017
A view prominently expounded is that the interaction between the composition and the volume of public expenditures is directly affected by political, institutional, psephological and ideological indicators.
Ebru Canikalp, Ilter Unlukaplan
doaj   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

open access: yesAdvanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang   +11 more
wiley   +1 more source

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