Results 131 to 140 of about 164,183 (315)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Competing impure public goods and the sustainability of the theater arts [PDF]

open access: yes
The general purpose of this paper is to extend the literature regarding public good provision when consumers may contribute via consumption of an impure public good and/or by donating directly to the public good.
Tyler Pugliese, Jeffrey Wagner
core  

Preferential opponent selection in public goods games [PDF]

open access: yes, 2012
This paper discusses preferential opponent selection in public goods games. It is shown that a preference to play with successful opponents strongly enhances the prevalence of cooperation. The finding is robust on spatial grids and heterogeneous networks.
Brede, Markus
core  

EVALUATION OF PUBLIC GOODS -THE COUNTERPOINTS AND CONTRADICTIONS OF THE CROATIAN CONCEPT OF ‘GOODS OF INTEREST TO THE REPUBLIC OF CROATIA’

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2009
In this paper the author analyses the dominant concept about ‘public things’ and in particular the question of the nature of public property. Also analysed are the viewpoints which see goods in public property as some kind of private property.
Branko Babac
doaj  

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Inducing a Self-Fulfilling Prophecy in Public Goods Games. [PDF]

open access: yes
This study explores how a self-fulfilling prophecy can solve a social dilemma. We ran two experimental treatments, baseline and automata. Both consisted of a finitely repeated public goods game with a surprise restart.
Enrique Fatas   +2 more
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

Lindahl Equilibrium and Schweitzer's Open Club Model Semi-Public Goods

open access: yes
Limit core allocations are the ones that remain in the core of a replicated economy.An equivalent notion for economies with public goods is Schweizer s concept of club e ciency under a variable number of economic agents.We extend this notion to economies
Raa, T. ten, Gilles, R.P.
core  

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