Results 121 to 130 of about 1,703,286 (308)

Public goods

open access: yes, 2019
Supplying public goods generates costs and benefits that can be allocated among individuals in different ways. Yet leading theories of justice within liberalism fail to offer concrete guidance on how these allocations should be assessed. This chapter critically examines a number of principles of distributive justice that might be used for this purpose.
Miller, D, Taylor, I
openaire   +1 more source

Competing impure public goods and the sustainability of the theater arts [PDF]

open access: yes
The general purpose of this paper is to extend the literature regarding public good provision when consumers may contribute via consumption of an impure public good and/or by donating directly to the public good.
Jeffrey Wagner, Tyler Pugliese
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Cheater-altruist synergy in immunopathogenic ecological public goods games

open access: yes, 2017
Much research has focused on the deleterious effects of free-riding in public goods games, and a variety of mechanisms that suppresses cheating behaviour. Here we argue that under certain conditions cheating behaviour can be beneficial to the population.
Morsky, Bryce, Vural, Dervis Can
core   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

INDIVIDUAL usE of general – usE goods in Croatia: Ranges and limitations

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2009
General- use goods are common goods in general usage. The use of general- use goods can be communal and individual. Communal use of general -use goods is anonymous and impersonal, free and equitable.
Damir Aviani
doaj  

Understanding the Challenges of the Digital Economy: The Nature of Digital Goods [PDF]

open access: yes
This article investigates the economic nature and characteristics of digital goods. Such goods are, due to their replicability, shown to be public goods (albeit in an evolutionary way) and durable goods.
Thierry RAYNA
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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