Results 111 to 120 of about 164,183 (315)

Money and Finance as Global Public Goods

open access: yesSAGE Open, 2011
The 2007-2008 financial crisis caused not only a dramatic fall in global output and employment but also a serious deterioration of public indebtedness for many governments, forced to rescue the banking system from failure. The crisis showed that national
Guido Montani
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Lotteries as a funding tool for financing public goods [PDF]

open access: yes
In the Review of Economic Studies, Morgan (2000) proposed that targeted self-funding lotteries could be used as a method of increasing voluntary contributions to public goods. In the same issue, Morgan and Sefton (2000) tested the theoretical predictions
Rob Moir
core  

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Optimal Income Taxation, Public Goods Provision and Robust Mechanism Design [PDF]

open access: yes
This paper extends the model of optimal income taxation due to Mirrlees (1971) and includes private information on public goods preferences. A mechanism design approach is used to establish the following result: If policies are required to be robustly ...
Felix Bierbrauer
core  

COVID-19 and territorial politics: towards a redefinition of Spanish intergovernmental relations?

open access: yesRegional Studies, Regional Science
When COVID-19 (coronavirus disease 2019) struck Spain, it caused a multidimensional crisis that sparked countless debates on its health, social and political implications.
Jorge Hernández-Moreno   +1 more
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Global and regional public goods: a prognosis for collective action [PDF]

open access: yes
This paper applies modern concepts from the theory of public goods to indicate why progress has been made with respect to some global and regional public goods (for example, cutting sulphur emissions) but not with respect to others (for example, cutting ...
Todd Sandler
core  

Economics as a Public Good

open access: yes, 1989
The paper is a contribution to a series of recollections and reflections on the professional experiences of distinguished economists which the Banca Nazionale del Lavoro Quarterly Review started in 1979. In it Herbert Giersch explains that economics is a pubic good with a potential demand far from saturation.
openaire   +2 more sources

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