Results 81 to 90 of about 3,011,326 (280)
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Factors related to the resignation and migration of physicians in public health administration agencies using nationwide survey data in Japan. [PDF]
BMC Health Serv Res, 2023 Saijo Y, Yoshioka E, Sato Y, Kunori Y.
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Corruption in the public organizations. Towards a model of cost-benefit analysis for the anticorruption strategies [PDF]
The paper aims to evaluate how the anticorruption strategies lead to minimizing the corruption phenomenon in the public organizations, with special reference to those from public administration and health system in Romania.
Matei, Ani, Matei, Lucica
core +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Arterial hypertension registry in Vologda Region
Кардиоваскулярная терапия и профилактика, 2007 Aim. To study implementation experience of arterial hypertension (AH) diagnostics, monitoring, and control technology in Vologda Region primary healthcare system. Material and methods.
A. I. Popugaev +5 more
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The relationship between budgetary expenditure and economic growth in Poland [PDF]
This paper investigates the association between different kinds of budgetary expenditure and economic growth of Poland. The empirical analysis makes use of linear and nonlinear Granger causality tests to evaluate the applicability of Wagner’s Law and ...
Gurgul, Henryk +2 more
core +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
SAGE Open Medicine, 2017 Objectives: HIV and other sexually transmitted infections remain a challenge globally and many key groups have yet to be studied. Evidence shows that truck drivers may have high-risk behaviors and higher sexually transmitted infection/HIV prevalence ...
Patricía J García +9 more
doaj +1 more source
Social Equity and COVID-19: The Case of African Americans [PDF]
, 2020 Emerging statistics demonstrate that COVID-19 disproportionately affects African Americans. The effects of COVID-19 for this population are inextricably linked to areas of systemic oppression and disenfranchisement, which are further exacerbated by COVID-
Merritt, Cullen C., Wright, James E.
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