Results 101 to 110 of about 5,645,039 (315)

Pilot study of a randomized trial to evaluate a Web-based intervention targeting adolescents presenting to the emergency department with acute asthma

Pilot and Feasibility Studies, 2017
Background Low-income African-American adolescents use preventive medical services less frequently than their White counterparts, indicating a need for effective interventions targeting this group.
Christine L. M. Joseph, Prashant Mahajan, Stephanie Stokes-Buzzelli, Dayna A. Johnson, Elizabeth Duffy, Renee Williams, Talan Zhang, Dennis R. Ownby, Shannon Considine, Mei Lu   +9 more
doaj   +1 more source

Young Adult Outcomes of Youth Exiting Dependent or Delinquent Care in Los Angeles County [PDF]

, 2011
Compares educational, employment, health, mental health, criminal justice, and public welfare outcomes for youth who age out of foster care, those who exit the juvenile probation system, and those who were involved in both systems.
Dennis P. Culhane, Halil Toros, Manuel Moreno, Max Stevens, Stephen Metraux, Thomas Byrne   +5 more
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Assessing the implementation of the public health emergency operations centre in Ethiopia, 2017–2023

Journal of Interventional Epidemiology and Public Health
Humanitarian crises and infectious diseases remain major global and national public health concerns, emphasizing the need for strong public health emergency management systems. Ethiopia established its Public Health Emergency Operations Centre (PHEOC) in
Shambel Habebe Watare, Mohammed Hasen Badeso, Addisu Daba Fufa, Zewdu Asefa Edea   +3 more
doaj   +1 more source

Assessing efficiency of public health and medical care provision in OECD countries after a decade of reform [PDF]

, 2017
The objective of this study was to examine the change in efficiency of health care systems of 34 OECD countries between 2000 and 2012, a period marked by significant health reform in most OECD countries.
Khushalani, Jaya, Ozcan, Yasar A.
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Validation of the consumer health activation index (CHAI) among community-dwelling adults in primary care clinics in Singapore

Population Health Metrics
Background Health activation is an individual’s knowledge, skills, and confidence in managing personal health and healthcare. The Consumer Health Activation Index (CHAI) is a freely available, 10-item measure originally developed in the United States ...
Justin Guang Jie Lee, Qin Xiang Ng, Nan Luo, Gerald Choon Huat Koh, Ling Jie Cheng   +4 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Association of a healthy ageing index with health-related outcomes in a multi-ethnic cohort from Singapore

BMC Geriatrics
Background The global population is ageing rapidly and it is important to promote healthy ageing. The Healthy Ageing Index (HAI) is a comprehensive measure of health, but there is limited research on its association with other age-related outcomes.
Nazira Binte Muhammad Fauzi, Xiangyuan Huang, Ling Jie Cheng, Nan Luo, Saima Hilal   +4 more
doaj   +1 more source