An Overview on Institutionalism and Decentralized Decision-Making [PDF]
, 2011 Human actions, interactions and decisions should have a certain degree of predictability that can be obtained by establishing rules. Institutions, in general, are defined by sets of rules known by the public and applicable for the community.
Forsberg, Michael +3 more
core +3 more sources
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Adherence to public institutions that foster cooperation. [PDF]
Nat Commun, 2021 Radzvilavicius AL +2 more
europepmc +1 more source
Noncooperative Support of Public Norm Enforcement in Large Societies [PDF]
In small groups norm enforcement is provided by mutual punishment and reward. In large societies we have enforcement institutions. This paper shows how such institutions can emerge as a decentralized equilibrium. In a first stage, individuals invest in a
Josef Falkinger
core
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Instituições de Suporte, Serviços e Desempenho: um Estudo em Aglomeração Turística de Santa Catarina [PDF]
RAC: Revista de Administração Contemporânea, 2013 The objective of this study was to evaluate clusters of tourism support institutions on the northern coast of the Brazilian state of Santa Catarina state.
Valmir Emil Hoffmann +1 more
doaj
The legal and institutional framework for the protection of religious rights in Nigeria and the right to wear Hijab in public institutions. [PDF]
F1000Res, 2023 Elikwu CM, Olujobi OJ, Yebisi ET.
europepmc +1 more source
Evaluating the Impact of the D.C. Tuition Assistance Grant Program [PDF]
In the Fall of 2000, the D.C. Tuition Assistance Grant program dramatically changed the menu of college prices offered to residents of the District of Columbia. The program allowed residents of D.C.
Thomas Kane
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Income distribution determinants and public spending efficiency [PDF]
In this paper we examine the impact of public spending, education, and institutions on income distribution in advanced economies. We also assess the efficiency of public spending in redistributing income by using a DEA (Data Envelopment Analysis ...
Afonso, António +2 more
core +3 more sources