Results 111 to 120 of about 23,082,987 (350)

Co-creating a patient and public involvement and engagement ‘how to’ guide for researchers

Research Involvement and Engagement, 2020
Plain language summary Research should benefit society at large. Involving citizens those who are affected by research may not only increase the quality, but can also push research towards generating greater societal benefits and relevant outcomes for ...
R. Kaisler, B. Missbach
semanticscholar   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Embedding Public Involvement in a PhD Research Project With People Affected by Advanced Liver Disease

Health Expectations
Background Liver disease is an increasing cause of morbidity and mortality in the United Kingdom and can be challenging to live with in the advanced stages.
Cathy J. Beresford, Mahabuba Rahman, Yvonne Gray, Sandra Ramshaw, Leslie Gelling, Sue Baron, Jackie Dominey   +6 more
doaj   +1 more source

CP-EXCEL:  A feasibility randomised controlled trial of an online exercise programme for adults with cerebral palsy [version 3; peer review: 2 approved]

HRB Open Research
Introduction Adults with cerebral palsy (CP) are at increased risk of non-communicable diseases and often experience secondary complications as they age. Physical activity can mitigate these risks and improve well-being.
Karen McConnell, Rebecca Walters, Aisling Walsh, Éabha Wall, Claire Kerr, Claire Kenny, Kevin Bravender, Jessica Burke, Rachel Byrne, Jennifer Ryan, Fiona Weldon, Pauline Hunter-Graham, Manjula Manikandan, Miriam Creeger, Ailish McGahey   +14 more
doaj   +1 more source

Patient and public involvement in palliative care research: What works, and why? A qualitative evaluation

Palliative Medicine, 2020
Background: Public involvement is increasingly considered a prerequisite for high-quality research. However, involvement in palliative care is impeded by limited evidence on the best approaches for populations affected by life-limiting illness.
Halle Johnson, M. Ogden, L. Brighton, S. Etkind, A. Oluyase, E. Chukwusa, Peihan Yu, S. de Wolf-Linder, Pam A. Smith, S. Bailey, J. Koffman, C. Evans   +11 more
semanticscholar   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Patient and Public Involvement of young people with a chronic condition in projects in health and social care: A scoping review

Health Expectations, 2020
The involvement of young people with a chronic condition in research and implementation projects in health and social care receives growing attention. Yet, there is a lack of conceptual clarity of this so‐called ‘Patient and Public Involvement’ (PPI) and
Femke van Schelven, H. Boeije, Veerle Mariën, J. Rademakers   +3 more
semanticscholar   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Involvement of patients or their representatives in quality management functions in EU hospitals:implementation and impact on patient-centred care strategies [PDF]

, 2014
OBJECTIVE: The objective of this study was to describe the involvement of patients or their representatives in quality management (QM) functions and to assess associations between levels of involvement and the implementation of patient-centred care ...
Kristensen, S, Ommen, O, Pfaff, H, Bottaro, S., Kringos, D.S., Wang, A., Lívio, A., Shaw, C., Plochg, T, Kristensen, S., Depaigne-Loth, A., Depaigne-Loth, A, Kutaj-Wasikowska, H, Kus, H, Secanell, M., Mannion, Russell, Ozturk, K., Bruneau, Charles, Leite, I, Botje, D, Groene, Oliver, Kutryba, B, Saillour-Glenisson, F, Garel, Pascal, Almeman, F., Lívio, A, Eiras, M, Wang, A, Franca, M, Thompson, Caroline A., Saluvan, M, Hammer, A., Almeman, F, Bartels, Paul, Jones, S., Kringos, DS, Secanell, M, Groene, O., Garel, P, Dersarkissian, Maral, Groene, O, Sunol, R., Kutaj-Wąsikowska, Halina, Leite, I., Lopez, MA, Arah, OA, Botje, Daan, Suñol Sala, Rosa, Thompson, Caroline A, Wagner, C, Kus, H., Vlcek, Frantisek, Klazinga, N. S., Franca, M., Escoval, Ana, Sunol, R, Plochg, T., Jones, S, Thompson, A, Car, M., DUQuE Project Consortium, Klazinga, Niek S, Wang, Aolin, Lombarts, M.J.M.H., Escoval, A, Eiras, M., Wagner, Cordula, Bartels, P, Chow, A., Shaw, C, Arah, Onyebuchi A, DerSarkissian, M, ?, ?, Klazinga, N, Klaus, E, Arah, Onyebuchi A., Bruneau, C, Vallejo, P., Thompson, A., Kutryba, B., Lombarts, MJMH, Car, M, Sunol, Rosa, Vlcek, F, Ommen, O., Saluvan, M., Thompson, CA, Klaus, E., Bottaro, S, Thompson, Andrew, Saillour-Glenisson, F., Vallejo, P, Lopez, M. A., Klazinga, Niek S., Mannion, R, Michel, P, Arah, Onyebuchi A.., Ozturk, K, Pfaff, H., Universitat Autònoma de Barcelona, Hammer, A, Michel, P.   +101 more
core   +1 more source

Consortium‐Based Patient and Public Involvement and Engagement for Long COVID Research: A Pirit‐Focused Impact Evaluation of the PHOSP‐COVID Study

Health Expectations
Background At the start of the coronavirus disease‐2019 (COVID‐19) pandemic in early 2020, the long‐term outcomes for survivors of COVID‐19 were unknown.
Linzy Houchen‐Wolloff, Joanna Bell, Rebecca Pritchard, Krisnah Poinasamy, Kate Holmes, Samantha Walker, Nikki Smith, Claire Hastie, Natalie Rogers, Dawn Adams, Rashmita Nathu, Rhyan Gill, Jenny Bunker, Lily Staunton, James Chalmers, Ling‐Pei Ho, Victoria Harris, Alexander Horsley, Michael Marks, Betty Raman, Louise V. Wain, Christopher Brightling, Rachael Evans   +22 more
doaj   +1 more source