Results 131 to 140 of about 23,082,987 (350)

Predicting involvement in prison gang activity: Street gang membership, social and psychological factors. [PDF]

, 2014
The aim of this study was to examine whether street gang membership, psychological factors, and social factors such as pre-prison experiences could predict young offenders’ involvement in prison gang activity.
Wood, Jane L., Alleyne, E., James, Mark, James, M., Ozcakir Mozova, K., Mozova, Katarina, Wood, J., Alleyne, Emma   +7 more
core   +1 more source

The 20 m shuttle run is not a valid test of cardiorespiratory fitness in boys aged 11–14 years

BMJ Open Sport & Exercise Medicine, 2019
Objectives The 20 m shuttle run test (20mSRT) is used to estimate cardiorespiratory fitness (CRF) through the prediction of peak oxygen uptake (V˙O2), but its validity as a measure of CRF during childhood and adolescence is questionable.
Jo Welsman, Neil Armstrong
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Guidance document: Evaluating public involvement in research [PDF]

, 2018
Public involvement (PI) in research has been steadily advancing in recent years. It has therefore, become increasingly important to evaluate PI in research to:- improve the quality of PI, and hence the quality of research - evidence the impact of PI and ...
Kok, Michele
core  

Patient and public involvement in health research in low and middle-income countries: a systematic review

BMJ Open, 2019
Objectives Patient and public involvement (PPI) is argued to lead to higher quality health research, which is more relatable to and helps empower the public.
N. Cook, N. Siddiqi, Maureen Twiddy, R. Kenyon   +3 more
semanticscholar   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Involvement of Ministries of Health in Health Service Coverage Decisions: Is England an Aberrant Case? [PDF]

, 1967
This article examines the involvement of ministries of health in making health service coverage decisions in Denmark, England, France and Germany. The study aims to inform debate in England about the feasibility of reducing perceived ministerial and ...
David Robertshaw, Canduela, Jesus, Young, DHJ, Knapp, Martin, Graham, Helen, Deeming, Christopher, Ettelt, S, Lewis, Jane, Brimblecombe, Nicola, Canduela, Jesus; id_orcid, Wittenberg, Raphael, Pickard, Linda, Damant, J, Lombard, Daniel, Mays, Nicholas, Lindsay, Colin, David Young, Powell, Catherine, Thomas, Theo, Robertshaw, D, de Vries, R, Ettelt, Stefanie, Christopher Deeming, Jo Ingold, Geiger, Ben Baumberg; id_orcid, Dave Beck, Gibbons, Andrea, Baumberg Geiger, B, Andrea Gibbons, Jackie Damant, Rebecca Taylor, Nolte, Ellen, Kate Summers, Will Bartlett, Young, D, Lorraine Williams, Scullion, Lisa, Ingold, J, Raeside, Robert, Lagarde, Mylene, Mays, N, Robert de Vries, Holly Sutherland, Williams, L, Catherine Powell, Ben Baumberg Geiger, De Agostini, Paula, De Agostini, P, Scullion, LC, Beck, Dave, Gough, Ian, Summers, K, Daniel Edmiston, Margaret Perkins, Stefanie Ettelt, Williams, Lorraine, Trigg, Lisa, Linda Pickard, Robertshaw, David, Tan, Stefanie, Macnicol, John, Summers, Kate, West, Anne, Sutherland, Holly, Thomson, Sarah, de Vries, Robert, Raphael Wittenberg, Scullion, L, Edmiston, Daniel, Perkins, Margaret, Greener, Ian, Theo Thomas, Geiger, Ben Baumberg, Sutherland, H, Lisa Scullion, Taylor, Rebecca, Hills, J, Wittenberg, R, Edmiston, D, Lewis, David, Baumberg Geiger, Ben, Isabel Shutes, Ingold, Jo, Perkins, M, Daniel Lombard, Ian Gough, Nikolentzos, Athanasios, Lombard, D, Nicholas Mays, Chevreul, Karine, Hills, John, Nicola Brimblecombe, Bartlett, Will, Gibbons, A, John Hills, Jane Lewis, Shutes, Isabel, Gibbons, AR, Damant, Jackie, King, Derek, Fraser, Alec, Derek King, Martin Knapp, Paola De Agostini, Young, David, Anne West, Fraser, A, Mays, NB, Lagarde, M, Alec Fraser, Stefanie Tan, Mylene Lagarde, Nicholas Mays, Tan, SM, Law, Alex, Mooney, Gerry   +112 more
core   +1 more source

“They are nae worrying about it… so …what’s the point in asking?”: A qualitative study of candidacy for early CKD care in areas of multiple deprivation

BMC Nephrology
Background Chronic kidney disease (CKD) is common, associated with substantial comorbidity and strong socioeconomic gradients. Early CKD care focuses on preventing disease progression and reducing cardiovascular risk. However, inequities in access to CKD
Buse Keskindag, Tom Blakeman, Audrey Hughes, Samira Bell, Mike Melvin, Fumiko Nakamaru, Melany Gray, Bhautesh Jani, Mhairi Mackenzie, Nicole Scholes-Robertson, Eilidh Cowan, Paul Cockwell, Simon Sawhney, Magdalena Rzewuska Diaz   +13 more
doaj   +1 more source

Does a Screening Trial for Spinal Cord Stimulation in Patients with Chronic Pain of Neuropathic Origin have Clinical Utility and Cost-Effectiveness? (TRIAL-STIM Study): study protocol for a randomised controlled trial

Trials, 2018
Background The TRIAL-STIM Study aims to assess the diagnostic performance, clinical outcomes and cost-effectiveness of a screening trial prior to full implantation of a spinal cord stimulation (SCS) device.
Sam Eldabe, Ashish Gulve, Simon Thomson, Ganesan Baranidharan, Rui Duarte, Susan Jowett, Harbinder Sandhu, Raymond Chadwick, Morag Brookes, Anisah Tariq, Jenny Earle, Jill Bell, Anu Kansal, Shelley Rhodes, Rod S. Taylor   +14 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source