Results 131 to 140 of about 725,840 (314)

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

A Rapid Evaluation of the Reporting and Publishing Practices of Patient and Public Involvement and Engagement in Health Research within a UK University Institute

open access: yes
Background Patient and Public Involvement and Engagement is important to ensure research addresses the issues that matter most to patients and the public. However, reporting and publishing of these activities is variable and inconsistent.
Ogden, M   +8 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Political efficacy, social network and involvement in public deliberation in rural China

open access: yes, 2017
This study examines the role of political efficacy and social networks in rural China to understand the social characteristics that might affect an individual’s disposition to join in public deliberations.
Pan, Yingchun   +5 more
core   +1 more source

“Starting to think that way from the start”: approaching deprescribing decision-making for people accessing palliative care - a qualitative exploration of healthcare professionals views

open access: yesBMC Palliative Care
Background Deprescribing has been defined as the planned process of reducing or stopping medications that may no longer be beneficial or are causing harm, with the goal of reducing medication burden while improving patient quality of life.
Anna Robinson-Barella   +10 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

What is going on in public involvement in health research? A qualitative exploration of aims, processes and outcomes [PDF]

open access: yes
This project aimed to understand what was going on in public involvement in health research based on an investigation of the relationship between the practice of involvement and conceptualisations of involvement in the literature.
Davies, Rosemary
core  

Practical guide: Patient and public involvement in antimicrobial medicines development research [PDF]

open access: yes, 2018
Patient and public involvement (PPI) in antimicrobial medicines development research is new and unfamiliar. There are few established patient support groups or voluntary organisations in the field of infection sciences given the short-term nature of many
Kok, Michele   +4 more
core  

Developing and evaluating guidelines for patient and public involvement (PPI) in research

open access: yes, 2015
© Emerald Group Publishing Limited Purpose – A growing literature reports the benefits and challenges of patient and public involvement (PPI) in research; nevertheless, understanding PPI in research design remains under-developed.
Donald, Christine   +5 more
core   +1 more source

Home - About - Disclaimer - Privacy