Results 71 to 80 of about 2,639,699 (314)
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Public involvement in health care
BMJ, 2004 The NHS needs to be clear about the aims and how to achieve them The government is promoting public involvement in health care as part of new NHS policy.1 2 Proposals include allowing the public to elect members of the governing boards of foundation trusts3 and primary care trusts' obligations to engage with the public.4 However, clarity and ...
Dominique, Florin, Jennifer, Dixon
openaire +3 more sources
Addressing the Intersections of Juvenile Justice Involvement and Youth Homelessness: Principles for Change [PDF]
, 2017 A young person's involvement with the justice system can increase their likelihood of later experiencing homelessness for many reasons, including the fact that educational disruptions and juvenile delinquency records can make it harder to obtain ...
Lisa Pilnik
core
Digital information and the 'privatisation of knowledge' [PDF]
, 2007 Purpose of this paper: To point out that past models of information ownership may not carry over to the age of digital information. The fact that public ownership of information (for example, by means of national and public library collections) created ...
Adobe +8 more
core +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Health ExpectationsBackground Liver disease is an increasing cause of morbidity and mortality in the United Kingdom and can be challenging to live with in the advanced stages.
Cathy J. Beresford +6 more
doaj +1 more source
A REVIEW ON PUBLIC PARTICIPATION IN ENVIRONMENTAL IMPACT ASSESSMENT IN MALAYSIA [PDF]
Environmental Impact Assessment (EIA) was introduced to measure the benefit or cost from physical development to the public and community. In Malaysia, EIA was initiated in 1988 as a mandatory legislative requirement to protect and enhance the quality of
Azizan MARZUKI
core
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source