Results 101 to 110 of about 6,675,706 (283)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Homomorphic public-key cryptosystems and encrypting boolean circuits

open access: yes, 2003
In this paper homomorphic cryptosystems are designed for the first time over any finite group. Applying Barrington's construction we produce for any boolean circuit of the logarithmic depth its encrypted simulation of a polynomial size over an ...
Grigoriev, Dima, Ponomarenko, Ilia
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

A Matrix Multiplication Approach to Quantum-Safe Cryptographic Systems

open access: yesCryptography
This paper introduces a novel approach based on matrix multiplication in Fpn×n, which enables methods for public key exchange, user authentication, digital signatures, blockchain integration, and homomorphic encryption. Unlike traditional algorithms that
Luis Adrián Lizama-Pérez
doaj   +1 more source

Computational Thinking Enrichment: Public-Key Cryptography

open access: yesInformatics in Education, 2018
The Computer Science Unplugged activities and project has been an influential STEM (Science, Technology, Engineering & Mathematics) initiative, providing enrichment and teaching activities supporting computational thinking.
Frances ROSAMOND
doaj   +1 more source

Soundness in the Public-Key Model [PDF]

open access: yes, 2001
The public-key model for interactive proofs has proved to be quite effective in improving protocol efficiency [CGGM00]. We argue, however, that its soundness notion is more subtle and complex than in the classical model, and that it should be better understood to avoid designing erroneous protocols. Specifically, for the public-key model, we - identify
Silvio Micali, Leonid Reyzin
openaire   +1 more source

Public-key cryptography and invariant theory

open access: yes, 2002
Public-key cryptosystems are suggested based on invariants of groups.
Grigoriev, D.
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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