Results 81 to 90 of about 6,586,318 (243)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

The Key Authority - Secure Key Management in Hierarchical Public Key Infrastructures

, 2004
We model a private key`s life cycle as a finite state machine. The states are the key`s phases of life and the transition functions describe tasks to be done with the key.
Karatsiolis, V., Lippert, M., Wiesmaier, A.   +2 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Computational Thinking Enrichment: Public-Key Cryptography

Informatics in Education, 2018
The Computer Science Unplugged activities and project has been an influential STEM (Science, Technology, Engineering & Mathematics) initiative, providing enrichment and teaching activities supporting computational thinking.
Frances ROSAMOND
doaj   +1 more source

Optimization of the multivariate polynomial public key for quantum safe digital signature. [PDF]

Sci Rep, 2023
Kuang R, Perepechaenko M.
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

A Matrix Multiplication Approach to Quantum-Safe Cryptographic Systems

Cryptography
This paper introduces a novel approach based on matrix multiplication in Fpn×n, which enables methods for public key exchange, user authentication, digital signatures, blockchain integration, and homomorphic encryption. Unlike traditional algorithms that
Luis Adrián Lizama-Pérez
doaj   +1 more source

Authenticated Public Key Elliptic Curve Based on Deep Convolutional Neural Network for Cybersecurity Image Encryption Application. [PDF]

Sensors (Basel), 2023
Hagras EAA, Aldosary S, Khaled H, Hassan TM.   +3 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

A Graph-Based Public-Key Cryptosystem Using the NP-Complete Problem of Partitioning Into Perfect Matchings

IEEE Access
Cryptography serves as the backbone of modern digital security, protecting sensitive information across electronic communication and transactions. The rapid advancement of quantum computing poses a threat to classical cryptographic systems, necessitating
Jane Shonon Cutinha, Swati Nayak, Sabitha D'Souza   +2 more
doaj   +1 more source