Results 81 to 90 of about 6,675,706 (283)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

FEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich   +7 more
wiley   +1 more source

RSA: A number of formulas to improve the search for p+qp+q

Journal of Mathematical Cryptology, 2017
Breaking RSA is one of the fundamental problems in cryptography. Due to its reliance on the difficulty of the integer factorization problem, no efficient solution has been found despite decades of extensive research. One of the possible ways to break RSA
Mohammed Ahmed, Alkhelaifi Abdulrahman
doaj   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, Volume 20, Issue 6, Page 1429-1452, June 2026.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Key distribution for heterogeneous public-key cryptosystems

Journal of Communications and Networks, 2013
The widespread use of cryptographic technologies is complicated by inconsistencies and duplication in the key management systems supporting their applications. The proliferation of key management systems or protocols also results in higher operational and infrastructure costs, and fails in interoperability.
Lv, Xixiang, Mu, Yi, Li, Hui
openaire   +1 more source

Quantum Resistant Random Linear Code Based Public Key Encryption Scheme RLCE [PDF]

, 2015
Lattice based encryption schemes and linear code based encryption schemes have received extensive attention in recent years since they have been considered as post-quantum candidate encryption schemes.
Wang, Yongge
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Parallel Key-Insulated Public Key Encryption [PDF]

, 2006
Security is constantly been infringed by inadvertent loss of secret keys, and as a solution, Dodis, Katz, Xu, and Yung [11], in Eurocrypt 2002, proposed a new paradigm called key-insulated security which provides tolerance against key exposures. Their scheme introduces a “helper key” which is used to periodically update the decryption key.
Goichiro Hanaoka, Yumiko Hanaoka, Hideki Imai   +2 more
openaire   +1 more source

The Key Authority - Secure Key Management in Hierarchical Public Key Infrastructures

, 2004
We model a private key`s life cycle as a finite state machine. The states are the key`s phases of life and the transition functions describe tasks to be done with the key.
Karatsiolis, V., Lippert, M., Wiesmaier, A.   +2 more
core   +1 more source