Results 41 to 50 of about 85,961 (310)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Using decision problems in public key cryptography [PDF]

open access: yes, 2007
There are several public key establishment protocols as well as complete public key cryptosystems based on allegedly hard problems from combinatorial (semi)group theory known by now.
Shpilrain, Vladimir, Zapata, Gabriel
core   +3 more sources

Quantum asymmetric cryptography with symmetric keys

open access: yes, 2008
Based on quantum encryption, we present a new idea for quantum public-key cryptography (QPKC) and construct a whole theoretical framework of a QPKC system.
A. Kawachi   +41 more
core   +1 more source

New approach to practical leakage-resilient public-key cryptography

open access: yesJournal of Mathematical Cryptology, 2020
We present a new approach to construct several leakage-resilient cryptographic primitives, including leakage-resilient public-key encryption (PKE) schemes, authenticated key exchange (AKE) protocols and low-latency key exchange (LLKE) protocols.
Chakraborty Suvradip   +2 more
doaj   +1 more source

A Design of Secure Communication Architecture Applying Quantum Cryptography

open access: yesJournal of Information Science Theory and Practice, 2022
Existing network cryptography systems are threatened by recent developments in quantum computing. For example, the Shor algorithm, which can be run on a quantum computer, is capable of overriding public key-based network cryptography systems in a short ...
Kyu-Seok Shim   +2 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Learning with Errors is easy with quantum samples

open access: yes, 2018
Learning with Errors is one of the fundamental problems in computational learning theory and has in the last years become the cornerstone of post-quantum cryptography.
Grilo, Alex B.   +2 more
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

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