Results 31 to 40 of about 939,121 (301)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
A general outlook on Turkish librarianship and libraries [PDF]
, 2008 Turkey has a rich book and library tradition going back centuries. This article presents an overview of Turkish libraries and librarianship by providing information specifically on the library tradition in Turkey, public and special libraries ...
Bayır, Didar +3 more
core +3 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
AFLI Indicators for Measuring Library Performance: An Analytical Developmental Study
Cybrarians Journal, 2018 The objective of this study is to provide improvement opportunities for the Arab Federation of Libraries and Information (AFLI) indicators to measure library performance.
Emad Abu Eid
doaj +1 more source
Question: where would you go to escape detection if you wanted to do something illegal on the Internet? Hint: shush! [PDF]
, 2009 The background to this paper is the introduction of public access IT facilities in public libraries. These facilities have seen recorded instances of misuse alongside weaknesses in checking identities of users and in explaining Acceptable Use Policies ...
Ferguson, Ian +3 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The Role of Rural Public Libraries in Empowering and Developing the Rural Community [PDF]
تحقیقات اطلاعرسانی و کتابخانههای عمومیPurpose: Despite being mostly small institutions, rural public libraries provide a wide range of services and programs in very different areas of life, including personal education, development of individual and civic skills of all citizens and filling ...
Shiva Yari, Mohammad Amin Bahrami
doaj
A Review on the Role of Digital Libraries in Promoting Health Literacy [PDF]
Taṣvīr-i salāmat, 2014 Background and objectives : Considering the importance of public health and its key role in reducing treatment costs, new ways can be established to promote the public health knowledge.
Parvin Abdolahzadeh
doaj
Cybrarians Journal, 2009 Libraries and the information services they provide on the Internet face a set of challenges imposed by rapid developments in information technology and remote communications.
Mohamed Helmy
doaj +1 more source