Results 31 to 40 of about 170,282 (312)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Public libraries in Turkey

open access: yesBIBLIOTHEK Forschung und Praxis, 2008
La Turquie regarde sur une longue tradition de bibliotheques. Les bibliotheques publiques sont administrees par le Ministere de la Culture et du Tourisme, Direction generale des bibliotheques et des editeurs en Turquie ou la population s'eleve a 71 millions reparties en 81 provinces en sept grandes regions geographiques.
openaire   +4 more sources

Public libraries in the "age of austerity": income generation and public library ethos [PDF]

open access: yesLibrary and Information Research, 2014
The budgets of Britain’s public services have been under sustained pressure and public libraries are no exception to public spending cuts in today’s “age of austerity”. Librarians increasingly try to supplement shrinking budgets by employing a variety of income generation methods. But are these methods always in line with the public library ethos? This
Pautz, Hartwig, Poulter, Alan
openaire   +3 more sources

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Functional requirements for bibliographic records: global experiences and future visions for library catalogs available via the Internet. 1

open access: yesCybrarians Journal, 2009
Libraries and the information services they provide on the Internet face a set of challenges imposed by rapid developments in information technology and remote communications.
Mohamed Helmy
doaj   +1 more source

The Analysis of the Structure of Scientific Collaboration Networks in Basic Medical Sciences in the Science Citation Index from 1996 to 2013 [PDF]

open access: yesبازیابی دانش و نظام‌های معنایی, 2016
The present study aimed to determine the levels of Iranian collaboration and to analyze scientific collaboration network in the area of basic medical sciences, in the Science Citation Index from 1996 to 2013.
Asghar Sattarzadeh   +2 more
doaj   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

A Review on the Role of Digital Libraries in Promoting Health Literacy [PDF]

open access: yesTaṣvīr-i salāmat, 2014
​Background and objectives : Considering the importance of public health and its key role in reducing treatment costs, new ways can be established to promote the public health knowledge.
Parvin Abdolahzadeh
doaj  

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