Results 41 to 50 of about 170,282 (312)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

The Role of Rural Public Libraries in Empowering and Developing the Rural Community [PDF]

open access: yesتحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی
Purpose: Despite being mostly small institutions, rural public libraries provide a wide range of services and programs in very different areas of life, including personal education, development of individual and civic skills of all citizens and filling ...
Shiva Yari, Mohammad Amin Bahrami
doaj  

Volunteering in libraries: survey on Romanian public libraries

open access: yesRevista Română de Biblioteconomie și Știința Informării, 2021
Libraries are a natural hotspot for volunteer work, they can act as both beneficiaries and organizers of volunteers and their work. Volunteer programs in the libraries cover an important range of possibilities, from basic library work (moving books ...
Mihai Constantinescu   +2 more
doaj   +1 more source

Theorizing Public Libraries as Public Spheres in Library and Information Science [PDF]

open access: yes, 2020
During the 21st century, library and information scholars have set out to theorize the role of public libraries as public spheres. Most of this research is engaging with Habermas’ early work on the structural transformation of the public sphere. Even though Habermas has continued to develop his theories on the public sphere and deliberative democracy ...
openaire   +3 more sources

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Functional requirements for bibliographic records: global experiences and future visions for library catalogs available via the Internet. 2

open access: yesCybrarians Journal, 2010
Libraries and the information services they provide on the Internet face a set of challenges imposed by rapid developments in information technology and remote communications. The direct search service in the library catalog is one of the most prominent
Mohamed Helmy
doaj   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

The relationship between knowledge management and organizational learning among public librarians: A case study of public librarians in Fars province [PDF]

open access: yesتحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2022
Purpose: The purpose of this study is to investigate the relationship between knowledge management and organizational learning among public librarians in Fars province.
Ahmad Shabani   +3 more
doaj  

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