Results 151 to 160 of about 447,036 (202)

GloPath: An Entity‐Centric Foundation Model for Glomerular Lesion Assessment and Clinicopathological Insights

open access: yesAdvanced Science, EarlyView.
An entity‐centric foundation model, GloPath, is introduced for comprehensive glomerular lesion assessment from routine renal biopsy images. Trained on over one million glomeruli, the framework enables robust lesion recognition, grading, and cross modality diag nosis, while uncovering large‐scale clinicopathological associations.
Qiming He   +28 more
wiley   +1 more source

NUDT21 Drives T‐Cell Acute Lymphoblastic Leukemia Through Dual Regulation of Alternative Polyadenylation and Transcriptional Activation

open access: yesAdvanced Science, EarlyView.
In summary, our study defines a coordinated oncogenic model in which NUDT21 integrates alternative polyadenylation–dependent UBE2D3 stabilization and transcriptional activation to sustain MYC‐driven T‐ALL cell survival, thereby establishing NUDT21 as a central regulatory node and a promising therapeutic target.
Conglian Qiu   +18 more
wiley   +1 more source

Endogenous Ceramide 24:1 Constrains Th17‐Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling

open access: yesAdvanced Science, EarlyView.
Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu   +11 more
wiley   +1 more source

Tailored Porous Bimetallic Nanozyme Platform for Full‐Cycle Therapeutics of Intestinal Ischemia/Reperfusion

open access: yesAdvanced Science, EarlyView.
ABSTRACT Intestinal ischemia/reperfusion (I/R) injury presents a biphasic pathology: an acute oxidative‐inflammatory phase leading to organ failure, and a recovery phase marked by mucosal dysfunction and bacterial translocation. The developed MPB@TA‐Cu‐Ma nanocomposite functions as a dual‐phase therapeutic platform with significant efficacy. It rapidly
Chenghao Qiu   +15 more
wiley   +1 more source

The Public Health Library

open access: yesAmerican Journal of Public Health and the Nations Health, 1950
openaire   +3 more sources

The Public Library in the Community: Governance and Funding

open access: yesMaine Policy Review, 2013
Barbara McDade
doaj  
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Public Library

2022
The image is from “Monuments of Memories for Our Times” series which is made with a dedicated consideration to the complexities inherent to the “monument.” In “public Library,” Sung explores documenting vacant community infrastructure as monument of current times to archive the impact of Covid-19.
openaire   +1 more source

Public Libraries

2016
The author, as part of a Master Thesis study, analyzes the impact public library services and programs have in the lives of local Mexican mothers with children attending school in the United States and provides suggestions on ways to improve outreach of services and support.
  +4 more sources

Library Publications

Library Review, 1973
This long awaited and welcome publication fills a gap in our comparative librarianship literature. The author, who has been associated with the subject for a number of years, analyses existing writings, draws on the experience of other comparative disciplines and puts forward some personal views with the aim to ‘describe and demonstrate deficiencies ...
openaire   +1 more source

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