Results 41 to 50 of about 3,518,500 (299)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Библиосфера, 2021 The present review and analytical article devoted to the III International Bibliographic Congress provides general information about the most acute problems of modern bibliographic activity and the Congress as a whole, offers points of view on the main ...
A. Е. Guskov +4 more
doaj
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
State promotion of local public goods: The case of public libraries, 1880-1929 [PDF]
, 2016 The public library movement of the late nineteenth and early twentieth centuries led to a significant expansion of library services across the United States.
Kevane, Michael J, Sundstrom, William A.
core +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Implementation and Application of a Generative AI Virtual Librarian
International Journal of LibrarianshipSince its transformation into Taiwan’s first national digital library in 2013, the National Library of Public Information (NLPI) has continuously adopted innovative technologies to advance intelligent services.
Yun-Fan Chen, Hsiang-Ping Ma
doaj +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Developing Marketing Strategies for Public Libraries
Marketing Libraries Journal, 2018 The objective of marketing is to demonstrate the unlimited possibilities an institution has to offer to its target audience. For public libraries, this means engaging current and new users to attend programs, use resources and view the library as a ...
Monica Sanchez +1 more
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