Results 41 to 50 of about 6,827,236 (342)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Leadership In The Public Library : Case Study In Tenteram City Public Library

open access: yesRecord and Library Journal, 2018
In the formal and informal organization, it is always found someone who is considered more prominent than others, who then appointed or designated as a leader.
Muhammad Irsyad Al Fatih, Luki Wijayanti
doaj   +1 more source

The Public Library as Resistive Space in the Neoliberal City

open access: yesCity & Community, 2019
With reduced hours, decaying infrastructure, and precariously positioned staff, local public libraries provide much needed services in cities devastated by inequality and slashed safety nets.
S. Aptekar
semanticscholar   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Bibliographic information in digital culture: on the discussion problems and the results of the III International Bibliographic Congress

open access: yesБиблиосфера, 2021
The present review and analytical article devoted to the III International Bibliographic Congress provides general information about the most acute problems of modern bibliographic activity and the Congress as a whole, offers points of view on the main ...
A. Е. Guskov   +4 more
doaj  

Public libraries in Turkey

open access: yesBIBLIOTHEK Forschung und Praxis, 2008
La Turquie regarde sur une longue tradition de bibliotheques. Les bibliotheques publiques sont administrees par le Ministere de la Culture et du Tourisme, Direction generale des bibliotheques et des editeurs en Turquie ou la population s'eleve a 71 millions reparties en 81 provinces en sept grandes regions geographiques.
openaire   +4 more sources

Public libraries in the "age of austerity": income generation and public library ethos [PDF]

open access: yesLibrary and Information Research, 2014
The budgets of Britain’s public services have been under sustained pressure and public libraries are no exception to public spending cuts in today’s “age of austerity”. Librarians increasingly try to supplement shrinking budgets by employing a variety of income generation methods. But are these methods always in line with the public library ethos? This
Pautz, Hartwig, Poulter, Alan
openaire   +3 more sources

Collaborative, Creative, Participative: Trends in Public Library Innovation

open access: yesPublic Library Quarterly, 2019
Innovation in public libraries has been concentrated in the areas of participation, making & creating, learning, new outreach and partnerships. These trends represent the emerging areas of strategic focus for public libraries and are strongly influencing
Kirstie Nicholson
semanticscholar   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

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