Results 61 to 70 of about 6,827,236 (342)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Public libraries and lifelong learning [PDF]

open access: yesPerspectives of Innovations, Economics and Business, 2014
This paper reports on the results of an empirical study of public librarians’ conception of how public libraries support lifelong learning, as well as the role of information literacy in relation to lifelong learning. Lifelong learning has become essential to all people in today’s information society as a result of easy and free access to information ...
Nielsen, Bo Gerner, Borlund, Pia
openaire   +3 more sources

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

Developing Marketing Strategies for Public Libraries

open access: yesMarketing Libraries Journal, 2018
The objective of marketing is to demonstrate the unlimited possibilities an institution has to offer to its target audience. For public libraries, this means engaging current and new users to attend programs, use resources and view the library as a ...
Monica Sanchez   +1 more
doaj  

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Public Libraries As Partners for Health [PDF]

open access: yesPreventing Chronic Disease, 2018
Public libraries are free and accessible to all and are centers of community engagement and education, making them logical choices as partners for improving population health. Library staff members routinely assist patrons with unmet health and social needs.We used a 100-question, self-administered web survey sent to all library directors listed in the
Heather Klusaritz   +6 more
openaire   +3 more sources

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

ALM – nowatorskie metryki wskaźników wpływu w publikacjach naukowych

open access: yesBiblioteka, 2015
Cytowania przytaczane w literaturze światowej, a ostatnio statystyki wykorzystania materiału naukowego dostarczające informacji na temat zainteresowania i oddźwięku, jakie zdobywają publikacje naukowe, nadal pozostają ważnymi wskaźnikami wpływu w ocenie ...
Martin Fenner, Jennifer Lin
doaj   +1 more source

UK public library roles and value: A focus group analysis

open access: yesJournal of Library and Information Sciences, 2018
Findings from a study of the advantages and disadvantages accrued by individuals from their public library use, and the impact of this on citizenship at individual and community levels, are presented.
L. Appleton   +3 more
semanticscholar   +1 more source

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