Results 61 to 70 of about 20,571,475 (296)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Analysis of the public entrepreneurship phenomenon in a Brazilian state
This study examined the role of public entrepreneurs established in a state of Brazil. As our research showed, public entrepreneurs can be considered an innovation in people management in public service.
Magnus Emmendoerfer +1 more
doaj
Este artigo descreve a experiência de aplicação da ferramenta de análise administrativa na modernização da gestão pública, especificamente na Terceira Vara da Infância e da Juventude da Comarca de Porto Alegre (RS).
Silvia Generali da Costa
doaj +1 more source
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Analysis of the Field of Public Management: A Response to Kelman, Thompson, Jones and Schedler [PDF]
This essay examines the field of public management as explicated in the dialogue between Kelman, Thompson, Jones and Schedler (2003) and others, from the perspective of the philosophy of science.
Candreva, Philip J.
core +1 more source
Objective: to identify weaknesses in the anti-crisis plan, approved by the RF government’s resolution No. 98-R dated 27 January 2015, and to propose measures for their elimination. Method: abstract-logical.
D. V. Manushin
doaj
The objectives of this study were to verify if students of Open University of Brazil approve of mobile learning (m-learning) initiatives, to identify the students' perspectives about m-learning, to develop a model of instructional design for m-learning
Otacilio Antunes Santana +1 more
doaj +1 more source
Managers and Public Hospital Performance
We study whether the quality of managers can affect public service provision in the context of public health. Using novel data from public hospitals in Chile, we show how the introduction of a competitive recruitment system and better pay for public hospital CEOs reduced hospital mortality by 8 percent.
Muñoz, Pablo, Otero, Cristóbal
openaire +3 more sources
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
A avaliação das universidades vem sendo defendida como instrumento necessário para elevar a qualificação institucional, promovendo a melhoria do ensino, da pesquisa, da extensão e de sua gestão.
Jonas Cardona Venturini +5 more
doaj +1 more source

