Results 71 to 80 of about 20,571,475 (296)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

PROBLEMS OF ТНЕ DEVELOPMENT OF RUSSIAN ARCTIC REGION

open access: yesRUDN Journal of Public Administration, 2015
The article deals with the pressing problems of public management of processes of development of the Arctic region of Russia. Displayed the conditions of exploitation, reveals the objective and subjective difficulties the organization of effective public
Michael J Kornilov
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

01 Considerations of Public Management Functions - the Example of the College of Art "Ciprian Porumbescu" Suceava

open access: yesInternational Journal of Social and Educational Innovation, 2019
This study presents the basic functions of public management and summarizes the main duties of a school principal, as determined by the rules of organization and operation of schools approved by Order No.
Ciprian Ionel HRETCANU
doaj  

Conditions for effective management of a public organization on the example of public primary schools

open access: yesNowoczesne Systemy Zarządzania
Research objectives and hypothesis/research questions The aim of the article is to attempt to determine the conditions for effective management of a public organization on the example of public primary schools.
Stanisława Jung-Konstanty
doaj   +1 more source

URBAN PUBLIC POLICY FOR NATURAL DISASTER RISK MANAGEMENT IN BLUMENAU-SC: PROCESSES AND ACTIVITIES, [PDF]

open access: yesAmbiente & Sociedade
The objective of this study was the analysis of urban public policy for natural disaster risk management in the city of Blumenau, Santa Catarina, Brazil.
RAFAELA VIEIRA   +2 more
doaj   +3 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

New Public Management and Corruption: IPMN Dialogue and Analysis [PDF]

open access: yes, 2014
The article explores potential interrelationships between New Public Management reforms in the public sector and corrupt behavior of public servants, politicians and/or private providers of public services.
Reichard, Christoph   +1 more
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

El Capital Informacional en la Gestión Pública. Una aproximación al análisis de redes

open access: yesRevista Enfoques, 2009
This work aims to reflect on the informational capital governance. To do this, we divide it into three parts. The first of these is devoted to a review of the new reading of public administration, analyzing the key elements that inspire new trends in ...
Freddy Maríñez Navarro
doaj  

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