Results 71 to 80 of about 11,473,731 (348)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Infrastructural media and public media

open access: yes, 2017
The first issue starts with a programmatic article by Erhard Schüttpelz about Infrastructural Media and Public Media in which he addresses some basic ideas of the Collaborative Research Center Media of Cooperation. He points out that practice theory cannot be reduced to the study of practices.
openaire   +3 more sources

Honeymoon, medical treatment or big business? An analysis of the meanings of the term “reproductive tourism” in German and Israeli public media discourses

open access: yesPhilosophy, Ethics, and Humanities in Medicine, 2013
Background/IntroductionInfertile couples that travel to another country for reproductive treatment do not refer to themselves as “reproductive tourists”. They might even be offended by this term. “Tourism” is a metaphor with hidden connotations.
Sharon Bassan, Merle A Michaelsen
semanticscholar   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Podcasting as Public Media: The Future of U.S. News, Public Affairs, and Educational Podcasts

open access: yesInternational Journal of Communication, 2020
This article identifies a U.S.-based podcasting ecology as public media and then examines the threats to its future. It first identifies characteristics of a set of podcasts in the United States that allow them to be usefully described as public ...
Patricia Aufderheide   +3 more
doaj   +2 more sources

Assessing The Influence of Media Ownership on Journalism Practice: A Case Study of ZNBC TV1 and ZNBC Radio 1

open access: yesJournal of Arts, Humanities and Social Science
Media play an important role of informing, entertaining and educating society. Its significance and influence whether electronic or print media plays an undeniable role in today’s world.
Natasha Mwalimu, Sycorax T. Ndhlovu
doaj   +1 more source

From analogue to digital scholarship: implications for science communication researchers [PDF]

open access: yes, 2010
Digital media have transformed the social practices of science communication. They have extended the number of channels that scientists, media professionals, other stakeholders and citizens use to communicate scientific information.
Holliman, Richard
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

A Pirâmide das RP: Os media sociais e o papel das Relações [PDF]

open access: yes, 2012
This paper explores the relationship between social media as tools used by public relations professionals and as part of the daily lives of organizations’ stakeholders, identifying emergent practices in public relations and confronting new perspectives,
Andrade, José Gabriel   +2 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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